pAAV-FLEX-SaCas9-U6-sgRNA Citations (3)
Originally described in: Conditional Single Vector CRISPR/SaCas9 Viruses for Efficient Mutagenesis in the Adult Mouse Nervous System.Hunker AC, Soden ME, Krayushkina D, Heymann G, Awatramani R, Zweifel LS Cell Rep. 2020 Mar 24;30(12):4303-4316.e6. doi: 10.1016/j.celrep.2020.02.092. PubMed Journal
Articles Citing pAAV-FLEX-SaCas9-U6-sgRNA
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| CRISPR/SaCas9 mutagenesis of stromal interaction molecule 1 in proopiomelanocortin neurons increases glutamatergic excitability and protects against diet-induced obesity. Qiu J, Bosch MA, Stincic TL, Hunker AC, Zweifel LS, Ronnekleiv OK, Kelly MJ. Mol Metab. 2022 Dec;66:101645. doi: 10.1016/j.molmet.2022.101645. Epub 2022 Nov 25. PubMed |
A genetic variant of fatty acid amide hydrolase (FAAH) exacerbates hormone-mediated orexigenic feeding in mice.
Balsevich G, Petrie GN, Heinz DE, Singh A, Aukema RJ, Hunker AC, Vecchiarelli HA, Yau H, Sticht M, Thompson RJ, Lee FS, Zweifel LS, Chelikani PK, Gassen NC, Hill MN.
Elife. 2023 Apr 11;12:e81919. doi: 10.7554/eLife.81919.
PubMed
Associated Plasmids |
| A mesocortical glutamatergic pathway modulates neuropathic pain independent of dopamine co-release. Li M, Yang G. Nat Commun. 2024 Jan 20;15(1):643. doi: 10.1038/s41467-024-45035-2. PubMed |
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