GFP-rab7 DN Citations (29)

Originally described in: Rab proteins mediate Golgi transport of caveola-internalized glycosphingolipids and correct lipid trafficking in Niemann-Pick C cells.
Choudhury A, Dominguez M, Puri V, Sharma DK, Narita K, Wheatley CL, Marks DL, Pagano RE J Clin Invest. 2002 Jun . 109(12):1541-50. PubMed Journal

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Articles Citing GFP-rab7 DN

Articles
ESCRT-dependent targeting of plasma membrane localized KCa3.1 to the lysosomes. Balut CM, Gao Y, Murray SA, Thibodeau PH, Devor DC. Am J Physiol Cell Physiol. 2010 Nov;299(5):C1015-27. doi: 10.1152/ajpcell.00120.2010. Epub 2010 Aug 18. PubMed
Orthobunyavirus entry into neurons and other mammalian cells occurs via clathrin-mediated endocytosis and requires trafficking into early endosomes. Hollidge BS, Nedelsky NB, Salzano MV, Fraser JW, Gonzalez-Scarano F, Soldan SS. J Virol. 2012 Aug;86(15):7988-8001. doi: 10.1128/JVI.00140-12. Epub 2012 May 23. PubMed
Japanese encephalitis virus infects neuronal cells through a clathrin-independent endocytic mechanism. Kalia M, Khasa R, Sharma M, Nain M, Vrati S. J Virol. 2013 Jan;87(1):148-62. doi: 10.1128/JVI.01399-12. Epub 2012 Oct 10. PubMed
Differential regulation of amyloid-beta endocytic trafficking and lysosomal degradation by apolipoprotein E isoforms. Li J, Kanekiyo T, Shinohara M, Zhang Y, LaDu MJ, Xu H, Bu G. J Biol Chem. 2012 Dec 28;287(53):44593-601. doi: 10.1074/jbc.M112.420224. Epub 2012 Nov 6. PubMed
Transcription factors MYOCD, SRF, Mesp1 and SMARCD3 enhance the cardio-inducing effect of GATA4, TBX5, and MEF2C during direct cellular reprogramming. Christoforou N, Chellappan M, Adler AF, Kirkton RD, Wu T, Addis RC, Bursac N, Leong KW. PLoS One. 2013 May 21;8(5):e63577. doi: 10.1371/journal.pone.0063577. Print 2013. PubMed
Induced pluripotent stem cell-derived cardiac progenitors differentiate to cardiomyocytes and form biosynthetic tissues. Christoforou N, Liau B, Chakraborty S, Chellapan M, Bursac N, Leong KW. PLoS One. 2013 Jun 13;8(6):e65963. doi: 10.1371/journal.pone.0065963. Print 2013. PubMed
Single continuous lumen formation in the zebrafish gut is mediated by smoothened-dependent tissue remodeling. Alvers AL, Ryan S, Scherz PJ, Huisken J, Bagnat M. Development. 2014 Mar;141(5):1110-9. doi: 10.1242/dev.100313. Epub 2014 Feb 6. PubMed
Central role for PICALM in amyloid-beta blood-brain barrier transcytosis and clearance. Zhao Z, Sagare AP, Ma Q, Halliday MR, Kong P, Kisler K, Winkler EA, Ramanathan A, Kanekiyo T, Bu G, Owens NC, Rege SV, Si G, Ahuja A, Zhu D, Miller CA, Schneider JA, Maeda M, Maeda T, Sugawara T, Ichida JK, Zlokovic BV. Nat Neurosci. 2015 Jul;18(7):978-87. doi: 10.1038/nn.4025. Epub 2015 May 25. PubMed
Select Rab GTPases Regulate the Pulmonary Endothelium via Endosomal Trafficking of VE-cadherin. Chichger H, Braza J, Duong H, Boni G, Harrington EO. Am J Respir Cell Mol Biol. 2015 Nov 9. PubMed
Transdifferentiation of human endothelial progenitors into smooth muscle cells. Ji H, Atchison L, Chen Z, Chakraborty S, Jung Y, Truskey GA, Christoforou N, Leong KW. Biomaterials. 2016 Apr;85:180-94. doi: 10.1016/j.biomaterials.2016.01.066. Epub 2016 Feb 3. PubMed
Rab7 induces clearance of alpha-synuclein aggregates. Dinter E, Saridaki T, Nippold M, Plum S, Diederichs L, Komnig D, Fensky L, May C, Marcus K, Voigt A, Schulz JB, Falkenburger BH. J Neurochem. 2016 Sep;138(5):758-74. doi: 10.1111/jnc.13712. Epub 2016 Aug 4. PubMed
Lys-63-linked Ubiquitination of gamma-Aminobutyric Acid (GABA), Type B1, at Multiple Sites by the E3 Ligase Mind Bomb-2 Targets GABAB Receptors to Lysosomal Degradation. Zemoura K, Trumpler C, Benke D. J Biol Chem. 2016 Oct 7;291(41):21682-21693. Epub 2016 Aug 29. PubMed
An L- to D-amino acid conversion in the cell penetrating peptide dfTAT influences proteolytic stability, endocytic uptake, and endosomal escape. Najjar K, Erazo-Oliveras A, Brock DJ, Wang TY, Pellois JP. J Biol Chem. 2016 Dec 6. pii: jbc.M116.759837. PubMed
Core Transcription Factors, MicroRNAs, and Small Molecules Drive Transdifferentiation of Human Fibroblasts Towards The Cardiac Cell Lineage. Christoforou N, Chakraborty S, Kirkton RD, Adler AF, Addis RC, Leong KW. Sci Rep. 2017 Jan 10;7:40285. doi: 10.1038/srep40285. PubMed
Efficient transdifferentiation of human dermal fibroblasts into skeletal muscle. Boularaoui SM, Abdel-Raouf KMA, Alwahab NSA, Kondash ME, Truskey GA, Teo JCM, Christoforou N. J Tissue Eng Regen Med. 2017 Jan 18. doi: 10.1002/term.2415. PubMed
Rab7A regulates tau secretion. Rodriguez L, Mohamed NV, Desjardins A, Lippe R, Fon EA, Leclerc N. J Neurochem. 2017 May;141(4):592-605. doi: 10.1111/jnc.13994. Epub 2017 Mar 29. PubMed
Negative regulation of EGFR signalling by the human folliculin tumour suppressor protein. Laviolette LA, Mermoud J, Calvo IA, Olson N, Boukhali M, Steinlein OK, Roider E, Sattler EC, Huang D, Teh BT, Motamedi M, Haas W, Iliopoulos O. Nat Commun. 2017 Jun 28;8:15866. doi: 10.1038/ncomms15866. PubMed
The endosomal neuronal proteins Nsg1/NEEP21 and Nsg2/P19 are itinerant, not resident proteins of dendritic endosomes. Yap CC, Digilio L, McMahon L, Winckler B. Sci Rep. 2017 Sep 5;7(1):10481. doi: 10.1038/s41598-017-07667-x. PubMed
Combined venetoclax and alvocidib in acute myeloid leukemia. Bogenberger J, Whatcott C, Hansen N, Delman D, Shi CX, Kim W, Haws H, Soh K, Lee YS, Peterson P, Siddiqui-Jain A, Weitman S, Stewart K, Bearss D, Mesa R, Warner S, Tibes R. Oncotarget. 2017 Nov 3;8(63):107206-107222. doi: 10.18632/oncotarget.22284. eCollection 2017 Dec 5. PubMed
The cellular uptake of angiogenin, an angiogenic and neurotrophic factor is through multiple pathways and largely dynamin independent. Ferguson R, Subramanian V. PLoS One. 2018 Feb 27;13(2):e0193302. doi: 10.1371/journal.pone.0193302. eCollection 2018. PubMed
FYCO1 mediates clearance of alpha-synuclein aggregates through a Rab7-dependent mechanism. Saridaki T, Nippold M, Dinter E, Roos A, Diederichs L, Fensky L, Schulz JB, Falkenburger BH. J Neurochem. 2018 Aug;146(4):474-492. doi: 10.1111/jnc.14461. Epub 2018 Jul 23. PubMed
Degradation of dendritic cargos requires Rab7-dependent transport to somatic lysosomes. Yap CC, Digilio L, McMahon LP, Garcia ADR, Winckler B. J Cell Biol. 2018 Sep 3;217(9):3141-3159. doi: 10.1083/jcb.201711039. Epub 2018 Jun 15. PubMed
Epigenetic silencing of tumor suppressor Par-4 promotes chemoresistance in recurrent breast cancer. Mabe NW, Fox DB, Lupo R, Decker AE, Phelps SN, Thompson JW, Alvarez JV. J Clin Invest. 2018 Oct 1;128(10):4413-4428. doi: 10.1172/JCI99481. Epub 2018 Aug 27. PubMed
Autism Spectrum Disorder Risk Factor Met Regulates the Organization of Inhibitory Synapses. Jeckel P, Kriebel M, Volkmer H. Front Mol Neurosci. 2021 May 13;14:659856. doi: 10.3389/fnmol.2021.659856. eCollection 2021. PubMed
Transdifferentiation of Human Fibroblasts into Skeletal Muscle Cells: Optimization and Assembly into Engineered Tissue Constructs through Biological Ligands. Abdel-Raouf KMA, Rezgui R, Stefanini C, Teo JCM, Christoforou N. Biology (Basel). 2021 Jun 16;10(6). pii: biology10060539. doi: 10.3390/biology10060539. PubMed
APOBEC Mutagenesis Inhibits Breast Cancer Growth through Induction of T cell-Mediated Antitumor Immune Responses. DiMarco AV, Qin X, McKinney BJ, Garcia NMG, Van Alsten SC, Mendes EA, Force J, Hanks BA, Troester MA, Owzar K, Xie J, Alvarez JV. Cancer Immunol Res. 2022 Jan;10(1):70-86. doi: 10.1158/2326-6066.CIR-21-0146. Epub 2021 Nov 18. PubMed
Hydrophobicity is a key determinant in the activity of arginine-rich cell penetrating peptides. Allen J, Pellois JP. Sci Rep. 2022 Sep 25;12(1):15981. doi: 10.1038/s41598-022-20425-y. PubMed
Downregulation of KEAP1 in melanoma promotes resistance to immune checkpoint blockade. Fox DB, Ebright RY, Hong X, Russell HC, Guo H, LaSalle TJ, Wittner BS, Poux N, Vuille JA, Toner M, Hacohen N, Boland GM, Sen DR, Sullivan RJ, Maheswaran S, Haber DA. NPJ Precis Oncol. 2023 Mar 2;7(1):25. doi: 10.1038/s41698-023-00362-3. PubMed
Collapse of late endosomal pH elicits a rapid Rab7 response via V-ATPase and RILP. Mulligan RJ, Magaj MM, Digilio L, Redemann S, Yap CC, Winckler B. bioRxiv [Preprint]. 2024 Feb 17:2023.10.24.563658. doi: 10.1101/2023.10.24.563658. PubMed

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