pRK-Myc-Smurf2 Citations (7)

Originally described in: Regulation of Smad degradation and activity by Smurf2, an E3 ubiquitin ligase.
Zhang Y, Chang C, Gehling DJ, Hemmati-Brivanlou A, Derynck R Proc Natl Acad Sci U S A. 2001 Jan 30. 98(3):974-9. PubMed Journal

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Articles Citing pRK-Myc-Smurf2

Articles
HECT E3 Ubiquitin Ligase Itch Functions as a Novel Negative Regulator of Gli-Similar 3 (Glis3) Transcriptional Activity. ZeRuth GT, Williams JG, Cole YC, Jetten AM. PLoS One. 2015 Jul 6;10(7):e0131303. doi: 10.1371/journal.pone.0131303. eCollection 2015. PubMed
P38alpha/JNK signaling restrains erythropoiesis by suppressing Ezh2-mediated epigenetic silencing of Bim. Hu P, Nebreda AR, Hanenberg H, Kinnebrew GH, Ivan M, Yoder MC, Filippi MD, Broxmeyer HE, Kapur R. Nat Commun. 2018 Aug 29;9(1):3518. doi: 10.1038/s41467-018-05955-2. PubMed
TTC3 contributes to TGF-beta1-induced epithelial-mesenchymal transition and myofibroblast differentiation, potentially through SMURF2 ubiquitylation and degradation. Kim JH, Ham S, Lee Y, Suh GY, Lee YS. Cell Death Dis. 2019 Jan 29;10(2):92. doi: 10.1038/s41419-019-1308-8. PubMed
Structural and Functional Characterization of Ubiquitin Variant Inhibitors of USP15. Teyra J, Singer AU, Schmitges FW, Jaynes P, Kit Leng Lui S, Polyak MJ, Fodil N, Krieger JR, Tong J, Schwerdtfeger C, Brasher BB, Ceccarelli DFJ, Moffat J, Sicheri F, Moran MF, Gros P, Eichhorn PJA, Lenter M, Boehmelt G, Sidhu SS. Structure. 2019 Apr 2;27(4):590-605.e5. doi: 10.1016/j.str.2019.01.002. Epub 2019 Jan 31. PubMed
ZFYVE21 is a complement-induced Rab5 effector that activates non-canonical NF-kappaB via phosphoinosotide remodeling of endosomes. Fang C, Manes TD, Liu L, Liu K, Qin L, Li G, Tobiasova Z, Kirkiles-Smith NC, Patel M, Merola J, Fu W, Liu R, Xie C, Tietjen GT, Nigrovic PA, Tellides G, Pober JS, Jane-Wit D. Nat Commun. 2019 May 21;10(1):2247. doi: 10.1038/s41467-019-10041-2. PubMed
OTUD4 enhances TGFbeta signalling through regulation of the TGFbeta receptor complex. Jaynes PW, Iyengar PV, Lui SKL, Tan TZ, Vasilevski N, Wright SCE, Verdile G, Jeyasekharan AD, Eichhorn PJA. Sci Rep. 2020 Sep 24;10(1):15725. doi: 10.1038/s41598-020-72791-0. PubMed
Identification of Smurf2 as a HIF-1alpha degrading E3 ubiquitin ligase. Zhao S, El-Deiry WS. Oncotarget. 2021 Sep 28;12(20):1970-1979. doi: 10.18632/oncotarget.28081. eCollection 2021 Sep 28. PubMed

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