Skip to main content
This website uses cookies to ensure you get the best experience. By continuing to use this site, you agree to the use of cookies.

Please note: Your browser does not support the features used on Addgene's website. You may not be able to create an account or request plasmids through this website until you upgrade your browser. Learn more

Please note: Your browser does not fully support some of the features used on Addgene's website. If you run into any problems registering, depositing, or ordering please contact us at [email protected]. Learn more

Addgene

SIRT4 Flag Citations (9)

Originally described in: The human Sir2 ortholog, SIRT2, is an NAD+-dependent tubulin deacetylase.
North BJ, Marshall BL, Borra MT, Denu JM, Verdin E Mol Cell. 2003 Feb . 11(2):437-44.
PubMed Journal

Articles Citing SIRT4 Flag

Articles
The ubiquitin ligase CHIP prevents SirT6 degradation through noncanonical ubiquitination. Ronnebaum SM, Wu Y, McDonough H, Patterson C. Mol Cell Biol. 2013 Nov;33(22):4461-72. doi: 10.1128/MCB.00480-13. Epub 2013 Sep 16. PubMed
Sirtuin 4 is a lipoamidase regulating pyruvate dehydrogenase complex activity. Mathias RA, Greco TM, Oberstein A, Budayeva HG, Chakrabarti R, Rowland EA, Kang Y, Shenk T, Cristea IM. Cell. 2014 Dec 18;159(7):1615-25. doi: 10.1016/j.cell.2014.11.046. PubMed
Sirtuin 4 Regulates Lipopolysaccharide Mediated Leydig Cell Dysfunction. Ramatchandirin B, Sadasivam M, Kannan A, Prahalathan C. J Cell Biochem. 2016 Apr;117(4):904-16. doi: 10.1002/jcb.25374. Epub 2015 Sep 22. PubMed
Acetylation of Mammalian ADA3 Is Required for Its Functional Roles in Histone Acetylation and Cell Proliferation. Mohibi S, Srivastava S, Bele A, Mirza S, Band H, Band V. Mol Cell Biol. 2016 Sep 12;36(19):2487-502. doi: 10.1128/MCB.00342-16. Print 2016 Oct 1. PubMed
SIRT2 deacetylase regulates the activity of GSK3 isoforms independent of inhibitory phosphorylation. Sarikhani M, Mishra S, Maity S, Kotyada C, Wolfgeher D, Gupta MP, Singh M, Sundaresan NR. Elife. 2018 Mar 5;7. pii: 32952. doi: 10.7554/eLife.32952. PubMed
Mitochondrial Sirtuin 4 Resolves Immune Tolerance in Monocytes by Rebalancing Glycolysis and Glucose Oxidation Homeostasis. Tao J, Zhang J, Ling Y, McCall CE, Liu TF. Front Immunol. 2018 Mar 9;9:419. doi: 10.3389/fimmu.2018.00419. eCollection 2018. PubMed
Interplay between protein acetylation and ubiquitination controls MCL1 protein stability. Shimizu K, Gi M, Suzuki S, North BJ, Watahiki A, Fukumoto S, Asara JM, Tokunaga F, Wei W, Inuzuka H. Cell Rep. 2021 Nov 9;37(6):109988. doi: 10.1016/j.celrep.2021.109988. PubMed
Sirtuin-1 sensitive lysine-136 acetylation drives phase separation and pathological aggregation of TDP-43. Garcia Morato J, Hans F, von Zweydorf F, Feederle R, Elsasser SJ, Skodras AA, Gloeckner CJ, Buratti E, Neumann M, Kahle PJ. Nat Commun. 2022 Mar 9;13(1):1223. doi: 10.1038/s41467-022-28822-7. PubMed
Tumor growth of neurofibromin-deficient cells is driven by decreased respiration and hampered by NAD(+) and SIRT3. Masgras I, Cannino G, Ciscato F, Sanchez-Martin C, Darvishi FB, Scantamburlo F, Pizzi M, Menga A, Fregona D, Castegna A, Rasola A. Cell Death Differ. 2022 Apr 7. pii: 10.1038/s41418-022-00991-4. doi: 10.1038/s41418-022-00991-4. PubMed

If you have published an article using this material, please email us at [email protected] to have your article added to this page.