Skip to main content
This website uses cookies to ensure you get the best experience. By continuing to use this site, you agree to the use of cookies.

Please note: Your browser does not support the features used on Addgene's website. You may not be able to create an account or request plasmids through this website until you upgrade your browser. Learn more

Please note: Your browser does not fully support some of the features used on Addgene's website. If you run into any problems registering, depositing, or ordering please contact us at [email protected]. Learn more

Paxillin-pEGFP Citations (23)

Originally described in: Differential dynamics of alpha 5 integrin, paxillin, and alpha-actinin during formation and disassembly of adhesions in migrating cells.
Laukaitis CM, Webb DJ, Donais K, Horwitz AF J Cell Biol. 2001 Jun 25. 153(7):1427-40.
PubMed Journal

Articles Citing Paxillin-pEGFP

Migrating fibroblasts reorient directionality by a metastable, PI3K-dependent mechanism. Welf ES, Ahmed S, Johnson HE, Melvin AT, Haugh JM. J Cell Biol. 2012 Apr 2;197(1):105-14. doi: 10.1083/jcb.201108152. PubMed
cAMP inhibits migration, ruffling and paxillin accumulation in focal adhesions of pancreatic ductal adenocarcinoma cells: effects of PKA and EPAC. Burdyga A, Conant A, Haynes L, Zhang J, Jalink K, Sutton R, Neoptolemos J, Costello E, Tepikin A. Biochim Biophys Acta. 2013 Dec;1833(12):2664-72. doi: 10.1016/j.bbamcr.2013.06.011. Epub 2013 Jun 22. PubMed
The role of Arp2/3 in growth cone actin dynamics and guidance is substrate dependent. San Miguel-Ruiz JE, Letourneau PC. J Neurosci. 2014 Apr 23;34(17):5895-908. doi: 10.1523/JNEUROSCI.0672-14.2014. PubMed
Mechanical checkpoint for persistent cell polarization in adhesion-naive fibroblasts. Bun P, Liu J, Turlier H, Liu Z, Uriot K, Joanny JF, Coppey-Moisan M. Biophys J. 2014 Jul 15;107(2):324-35. doi: 10.1016/j.bpj.2014.05.041. PubMed
F-actin bundles direct the initiation and orientation of lamellipodia through adhesion-based signaling. Johnson HE, King SJ, Asokan SB, Rotty JD, Bear JE, Haugh JM. J Cell Biol. 2015 Feb 16;208(4):443-55. doi: 10.1083/jcb.201406102. Epub 2015 Feb 9. PubMed
Formin 2 regulates the stabilization of filopodial tip adhesions in growth cones and affects neuronal outgrowth and pathfinding in vivo. Sahasrabudhe A, Ghate K, Mutalik S, Jacob A, Ghose A. Development. 2016 Feb 1;143(3):449-60. doi: 10.1242/dev.130104. Epub 2015 Dec 30. PubMed
Epithelial- mesenchymal transition, IP3 receptors and ER-PM junctions: translocation of Ca2+ signalling complexes and regulation of migration. Okeke E, Parker T, Dingsdale H, Concannon M, Awais M, Voronina SG, Molgo J, Begg M, Metcalf D, Knight AE, Sutton R, Haynes LP, Tepikin AV. Biochem J. 2016 Jan 12. pii: BJ20150364. PubMed
Activity-dependent dephosphorylation of paxillin contributed to nociceptive plasticity in spinal cord dorsal horn. Wang XT, Zheng R, Suo ZW, Liu YN, Zhang ZY, Ma ZA, Xue Y, Xue M, Yang X, Hu XD. Pain. 2016 Mar;157(3):652-65. doi: 10.1097/j.pain.0000000000000415. PubMed
FMN2 Makes Perinuclear Actin to Protect Nuclei during Confined Migration and Promote Metastasis. Skau CT, Fischer RS, Gurel P, Thiam HR, Tubbs A, Baird MA, Davidson MW, Piel M, Alushin GM, Nussenzweig A, Steeg PS, Waterman CM. Cell. 2016 Dec 1;167(6):1571-1585.e18. doi: 10.1016/j.cell.2016.10.023. Epub 2016 Nov 10. PubMed
Calpain-mediated proteolysis of Talin and FAK regulates adhesion dynamics necessary for axon guidance. Kerstein PC, Patel KM, Gomez TM. J Neurosci. 2017 Jan 9. pii: 2769-16. doi: 10.1523/JNEUROSCI.2769-16.2016. PubMed
Integrin-mediated traction force enhances paxillin molecular associations and adhesion dynamics that increase the invasiveness of tumor cells into a three-dimensional extracellular matrix. Mekhdjian AH, Kai F, Rubashkin MG, Prahl LS, Przybyla LM, McGregor AL, Bell ES, Barnes JM, DuFort CC, Ou G, Chang AC, Cassereau L, Tan SJ, Pickup MW, Lakins JN, Ye X, Davidson MW, Lammerding J, Odde DJ, Dunn AR, Weaver VM. Mol Biol Cell. 2017 Jun 1;28(11):1467-1488. doi: 10.1091/mbc.E16-09-0654. Epub 2017 Apr 5. PubMed
Endosomal sorting and c-Cbl targeting of paxillin to autophagosomes regulate cell-matrix adhesion turnover in human breast cancer cells. Chang CH, Bijian K, Qiu D, Su J, Saad A, Dahabieh MS, Miller WH Jr, Alaoui-Jamali MA. Oncotarget. 2017 May 9;8(19):31199-31214. doi: 10.18632/oncotarget.16105. PubMed
Contact guidance persists under myosin inhibition due to the local alignment of adhesions and individual protrusions. Kubow KE, Shuklis VD, Sales DJ, Horwitz AR. Sci Rep. 2017 Oct 30;7(1):14380. doi: 10.1038/s41598-017-14745-7. PubMed
Focal Adhesions Undergo Longitudinal Splitting into Fixed-Width Units. Young LE, Higgs HN. Curr Biol. 2018 Jul 9;28(13):2033-2045.e5. doi: 10.1016/j.cub.2018.04.073. Epub 2018 Jun 14. PubMed
Identification of a novel anoikis signalling pathway using the fungal virulence factor gliotoxin. Haun F, Neumann S, Peintner L, Wieland K, Habicht J, Schwan C, Ostevold K, Koczorowska MM, Biniossek M, Kist M, Busch H, Boerries M, Davis RJ, Maurer U, Schilling O, Aktories K, Borner C. Nat Commun. 2018 Aug 30;9(1):3524. doi: 10.1038/s41467-018-05850-w. PubMed
Talin Autoinhibition Regulates Cell-ECM Adhesion Dynamics and Wound Healing In Vivo. Haage A, Goodwin K, Whitewood A, Camp D, Bogutz A, Turner CT, Granville DJ, Lefebvre L, Plotnikov S, Goult BT, Tanentzapf G. Cell Rep. 2018 Nov 27;25(9):2401-2416.e5. doi: 10.1016/j.celrep.2018.10.098. PubMed
Actomyosin contractility-dependent matrix stretch and recoil induces rapid cell migration. Wang WY, Davidson CD, Lin D, Baker BM. Nat Commun. 2019 Mar 12;10(1):1186. doi: 10.1038/s41467-019-09121-0. PubMed
Altering integrin engagement regulates membrane localization of Kir2.1 channels. Sengupta S, Rothenberg KE, Li H, Hoffman BD, Bursac N. J Cell Sci. 2019 Sep 2;132(17). pii: jcs.225383. doi: 10.1242/jcs.225383. PubMed
Multiparametric Analysis of Focal Adhesions in Bidimensional Substrates. Talayero VC, Vicente-Manzanares M. Methods Mol Biol. 2021;2217:27-37. doi: 10.1007/978-1-0716-0962-0_3. PubMed
ORAI2 Promotes Gastric Cancer Tumorigenicity and Metastasis through PI3K/Akt Signaling and MAPK-Dependent Focal Adhesion Disassembly. Wu S, Chen M, Huang J, Zhang F, Lv Z, Jia Y, Cui YZ, Sun LZ, Wang Y, Tang Y, Verhoeft KR, Li Y, Qin Y, Lin X, Guan XY, Lam KO. Cancer Res. 2021 Feb 15;81(4):986-1000. doi: 10.1158/0008-5472.CAN-20-0049. Epub 2020 Dec 11. PubMed
Vimentin tunes cell migration on collagen by controlling beta1 integrin activation and clustering. Ostrowska-Podhorodecka Z, Ding I, Lee W, Tanic J, Abbasi S, Arora PD, Liu RS, Patteson AE, Janmey PA, McCulloch CA. J Cell Sci. 2021 Mar 29;134(6). pii: jcs.254359. doi: 10.1242/jcs.254359. PubMed
Local synthesis of the phosphatidylinositol-3,4-bisphosphate lipid drives focal adhesion turnover. Posor Y, Kampyli C, Bilanges B, Ganguli S, Koch PA, Wallroth A, Morelli D, Jenkins M, Alliouachene S, Deltcheva E, Baum B, Haucke V, Vanhaesebroeck B. Dev Cell. 2022 Jul 25;57(14):1694-1711.e7. doi: 10.1016/j.devcel.2022.06.011. Epub 2022 Jul 8. PubMed
A Programmable DNA Origami Nanospring That Reports Dynamics of Single Integrin Motion, Force Magnitude and Force Orientation in Living Cells. Matsubara H, Fukunaga H, Saito T, Ikezaki K, Iwaki M. ACS Nano. 2023 Jul 25;17(14):13185-13194. doi: 10.1021/acsnano.2c12545. Epub 2023 Jul 2. PubMed

If you have published an article using this material, please email us at [email protected] to have your article added to this page.