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pLCHKO Citations (2)

Originally described in: Genetic interaction mapping and exon-resolution functional genomics with a hybrid Cas9-Cas12a platform.
Gonatopoulos-Pournatzis T, Aregger M, Brown KR, Farhangmehr S, Braunschweig U, Ward HN, Ha KCH, Weiss A, Billmann M, Durbic T, Myers CL, Blencowe BJ, Moffat J Nat Biotechnol. 2020 May;38(5):638-648. doi: 10.1038/s41587-020-0437-z. Epub 2020 Mar 16.
PubMed Journal

Articles Citing pLCHKO

Articles
Genome-scale exon perturbation screens uncover exons critical for cell fitness. Xiao MS, Damodaran AP, Kumari B, Dickson E, Xing K, On TA, Parab N, King HE, Perez AR, Guiblet WM, Duncan G, Che A, Chari R, Andresson T, Vidigal JA, Weatheritt RJ, Aregger M, Gonatopoulos-Pournatzis T. Mol Cell. 2024 Jul 11;84(13):2553-2572.e19. doi: 10.1016/j.molcel.2024.05.024. Epub 2024 Jun 24. PubMed

Associated Plasmids

A genome-wide functional analysis of conserved intronic regions reveals essential roles for speckle-associated retained introns. Farhangmehr S, Braunschweig U, Wu M, Nabeel-Shah S, Brown KR, Fine JL, Moffat J, Blencowe BJ. Cell Rep. 2026 Jul 28;45(7):117696. doi: 10.1016/j.celrep.2026.117696. Epub 2026 Jul 20. PubMed

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