Skip to main content
This website uses cookies to ensure you get the best experience. By continuing to use this site, you agree to the use of cookies.

Please note: Your browser does not support the features used on Addgene's website. You may not be able to create an account or request plasmids through this website until you upgrade your browser. Learn more

Please note: Your browser does not fully support some of the features used on Addgene's website. If you run into any problems registering, depositing, or ordering please contact us at [email protected]. Learn more

Addgene

pAMPK alpha2 K45R Citations (21)

Originally described in: A role for AMP-activated protein kinase in contraction- and hypoxia-regulated glucose transport in skeletal muscle.
Mu J, Brozinick JT, Valladares O, Bucan M, Birnbaum MJ Mol Cell. 2001 May . 7(5):1085-94.
PubMed Journal

Articles Citing pAMPK alpha2 K45R

Articles
AMPK inhibits myoblast differentiation through a PGC-1alpha-dependent mechanism. Williamson DL, Butler DC, Alway SE. Am J Physiol Endocrinol Metab. 2009 Aug;297(2):E304-14. doi: 10.1152/ajpendo.91007.2008. Epub 2009 Jun 2. PubMed
AMP-activated protein kinase (AMPK) cross-talks with canonical Wnt signaling via phosphorylation of beta-catenin at Ser 552. Zhao J, Yue W, Zhu MJ, Sreejayan N, Du M. Biochem Biophys Res Commun. 2010 Apr 23;395(1):146-51. doi: 10.1016/j.bbrc.2010.03.161. Epub 2010 Mar 31. PubMed
AMP-activated protein kinase regulates beta-catenin transcription via histone deacetylase 5. Zhao JX, Yue WF, Zhu MJ, Du M. J Biol Chem. 2011 May 6;286(18):16426-34. doi: 10.1074/jbc.M110.199372. Epub 2011 Mar 17. PubMed
The laforin-malin complex negatively regulates glycogen synthesis by modulating cellular glucose uptake via glucose transporters. Singh PK, Singh S, Ganesh S. Mol Cell Biol. 2012 Feb;32(3):652-63. doi: 10.1128/MCB.06353-11. Epub 2011 Nov 28. PubMed
AMP-activated protein kinase stimulates myostatin expression in C2C12 cells. Das AK, Yang QY, Fu X, Liang JF, Duarte MS, Zhu MJ, Trobridge GD, Du M. Biochem Biophys Res Commun. 2012 Oct 12;427(1):36-40. doi: 10.1016/j.bbrc.2012.08.138. Epub 2012 Sep 6. PubMed
Oleate prevents saturated-fatty-acid-induced ER stress, inflammation and insulin resistance in skeletal muscle cells through an AMPK-dependent mechanism. Salvado L, Coll T, Gomez-Foix AM, Salmeron E, Barroso E, Palomer X, Vazquez-Carrera M. Diabetologia. 2013 Jun;56(6):1372-82. doi: 10.1007/s00125-013-2867-3. Epub 2013 Mar 5. PubMed
Calcineurin suppresses AMPK-dependent cytoprotective autophagy in cardiomyocytes under oxidative stress. He H, Liu X, Lv L, Liang H, Leng B, Zhao D, Zhang Y, Du Z, Chen X, Li S, Lu Y, Shan H. Cell Death Dis. 2014 Jan 16;5:e997. doi: 10.1038/cddis.2013.533. PubMed
Metabolic-stress-induced rearrangement of the 14-3-3zeta interactome promotes autophagy via a ULK1- and AMPK-regulated 14-3-3zeta interaction with phosphorylated Atg9. Weerasekara VK, Panek DJ, Broadbent DG, Mortenson JB, Mathis AD, Logan GN, Prince JT, Thomson DM, Thompson JW, Andersen JL. Mol Cell Biol. 2014 Dec;34(24):4379-88. doi: 10.1128/MCB.00740-14. Epub 2014 Sep 29. PubMed
Regulation of Pancreatic beta Cell Mass by Cross-Interaction between CCAAT Enhancer Binding Protein beta Induced by Endoplasmic Reticulum Stress and AMP-Activated Protein Kinase Activity. Matsuda T, Takahashi H, Mieda Y, Shimizu S, Kawamoto T, Matsuura Y, Takai T, Suzuki E, Kanno A, Koyanagi-Kimura M, Asahara S, Bartolome A, Yokoi N, Inoue H, Ogawa W, Seino S, Kido Y. PLoS One. 2015 Jun 19;10(6):e0130757. doi: 10.1371/journal.pone.0130757. eCollection 2015. PubMed
Metformin Improves Ileal Epithelial Barrier Function in Interleukin-10 Deficient Mice. Xue Y, Zhang H, Sun X, Zhu MJ. PLoS One. 2016 Dec 21;11(12):e0168670. doi: 10.1371/journal.pone.0168670. eCollection 2016. PubMed
AMPK improves gut epithelial differentiation and barrier function via regulating Cdx2 expression. Sun X, Yang Q, Rogers CJ, Du M, Zhu MJ. Cell Death Differ. 2017 May;24(5):819-831. doi: 10.1038/cdd.2017.14. Epub 2017 Feb 24. PubMed
Hypoxia reduces HNF4alpha/MODY1 protein expression in pancreatic beta-cells by activating AMP-activated protein kinase. Sato Y, Tsuyama T, Sato C, Karim MF, Yoshizawa T, Inoue M, Yamagata K. J Biol Chem. 2017 May 26;292(21):8716-8728. doi: 10.1074/jbc.M116.767574. Epub 2017 Mar 31. PubMed
Entosis Is Induced by Glucose Starvation. Hamann JC, Surcel A, Chen R, Teragawa C, Albeck JG, Robinson DN, Overholtzer M. Cell Rep. 2017 Jul 5;20(1):201-210. doi: 10.1016/j.celrep.2017.06.037. PubMed
AMPK-Akt Double-Negative Feedback Loop in Breast Cancer Cells Regulates Their Adaptation to Matrix Deprivation. Saha M, Kumar S, Bukhari S, Balaji SA, Kumar P, Hindupur SK, Rangarajan A. Cancer Res. 2018 Mar 15;78(6):1497-1510. doi: 10.1158/0008-5472.CAN-17-2090. Epub 2018 Jan 16. PubMed
Adiponectin/T-cadherin system enhances exosome biogenesis and decreases cellular ceramides by exosomal release. Obata Y, Kita S, Koyama Y, Fukuda S, Takeda H, Takahashi M, Fujishima Y, Nagao H, Masuda S, Tanaka Y, Nakamura Y, Nishizawa H, Funahashi T, Ranscht B, Izumi Y, Bamba T, Fukusaki E, Hanayama R, Shimada S, Maeda N, Shimomura I. JCI Insight. 2018 Apr 19;3(8). pii: 99680. doi: 10.1172/jci.insight.99680. eCollection 2018 Apr 19. PubMed
Dishevelled has a YAP nuclear export function in a tumor suppressor context-dependent manner. Lee Y, Kim NH, Cho ES, Yang JH, Cha YH, Kang HE, Yun JS, Cho SB, Lee SH, Paclikova P, Radaszkiewicz TW, Bryja V, Kang CG, Yuk YS, Cha SY, Kim SY, Kim HS, Yook JI. Nat Commun. 2018 Jun 12;9(1):2301. doi: 10.1038/s41467-018-04757-w. PubMed
AMP-Activated Protein Kinase Is Essential for the Maintenance of Energy Levels during Synaptic Activation. Marinangeli C, Didier S, Ahmed T, Caillerez R, Domise M, Laloux C, Begard S, Carrier S, Colin M, Marchetti P, Ghesquiere B, Balschun D, Buee L, Kluza J, Vingtdeux V. iScience. 2018 Nov 30;9:1-13. doi: 10.1016/j.isci.2018.10.006. Epub 2018 Oct 12. PubMed
Protective autophagy elicited by RAF-->MEK-->ERK inhibition suggests a treatment strategy for RAS-driven cancers. Kinsey CG, Camolotto SA, Boespflug AM, Guillen KP, Foth M, Truong A, Schuman SS, Shea JE, Seipp MT, Yap JT, Burrell LD, Lum DH, Whisenant JR, Gilcrease GW 3rd, Cavalieri CC, Rehbein KM, Cutler SL, Affolter KE, Welm AL, Welm BE, Scaife CL, Snyder EL, McMahon M. Nat Med. 2019 Apr;25(4):620-627. doi: 10.1038/s41591-019-0367-9. Epub 2019 Mar 4. PubMed
YAP1 nuclear efflux and transcriptional reprograming follow membrane diminution upon VSV-G-induced cell fusion. Feliciano D, Ott CM, Espinosa-Medina I, Weigel AV, Benedetti L, Milano KM, Tang Z, Lee T, Kliman HJ, Guller SM, Lippincott-Schwartz J. Nat Commun. 2021 Jul 23;12(1):4502. doi: 10.1038/s41467-021-24708-2. PubMed
AMP-activated protein kinase inhibition in fibro-adipogenic progenitors impairs muscle regeneration and increases fibrosis. Liu X, Zhao L, Gao Y, Chen Y, Tian Q, Son JS, Chae SA, de Avila JM, Zhu MJ, Du M. J Cachexia Sarcopenia Muscle. 2023 Feb;14(1):479-492. doi: 10.1002/jcsm.13150. Epub 2022 Dec 13. PubMed
Redefining the role of AMPK in autophagy and the energy stress response. Park JM, Lee DH, Kim DH. Nat Commun. 2023 May 24;14(1):2994. doi: 10.1038/s41467-023-38401-z. PubMed

If you have published an article using this material, please email us at [email protected] to have your article added to this page.