Skip to main content
Holiday Schedule: Addgene will be closed November 24th & 25th for the Thanksgiving Holiday. Order processing and shipping may be delayed during this week. For questions about estimated ship dates, please feel free to track your order status or contact [email protected].
This website uses cookies to ensure you get the best experience. By continuing to use this site, you agree to the use of cookies.

Please note: Your browser does not support the features used on Addgene's website. You may not be able to create an account or request plasmids through this website until you upgrade your browser. Learn more

Please note: Your browser does not fully support some of the features used on Addgene's website. If you run into any problems registering, depositing, or ordering please contact us at [email protected] Learn more

pSin-EF2-Sox2-Pur Citations (32)

Plasmid Article: Induced pluripotent stem cell lines derived from human somatic cells.
Yu J, Vodyanik MA, Smuga-Otto K, Antosiewicz-Bourget J, Frane JL, Tian S, Nie J, Jonsdottir GA, Ruotti V, Stewart R, Slukvin II, Thomson JA Science. 2007 Dec 21. 318(5858):1917-20.
PubMed Journal

Articles Citing pSin-EF2-Sox2-Pur

Articles
Gene delivery efficiency in bone marrow-derived dendritic cells: comparison of four methods and optimization for lentivirus transduction. Li GB, Lu GX. Mol Biotechnol. 2009 Nov;43(3):250-6. doi: 10.1007/s12033-009-9197-1. Epub 2009 Jul 14. PubMed
Reprogramming of human fibroblasts to pluripotent stem cells using mRNA of four transcription factors. Yakubov E, Rechavi G, Rozenblatt S, Givol D. Biochem Biophys Res Commun. 2010 Mar 26. 394(1):189-93. PubMed
Engineering of human pluripotent stem cells by AAV-mediated gene targeting. Khan IF, Hirata RK, Wang PR, Li Y, Kho J, Nelson A, Huo Y, Zavaljevski M, Ware C, Russell DW. Mol Ther. 2010 Jun;18(6):1192-9. doi: 10.1038/mt.2010.55. Epub 2010 Apr 20. PubMed
Effects of estrogen on the proportion of stem cells in the breast. Simoes BM, Piva M, Iriondo O, Comaills V, Lopez-Ruiz JA, Zabalza I, Mieza JA, Acinas O, Vivanco MD. Breast Cancer Res Treat. 2011 Aug;129(1):23-35. doi: 10.1007/s10549-010-1169-4. Epub 2010 Sep 22. PubMed
Efficient preparation and labeling of human induced pluripotent stem cells by nanotechnology. Ruan J, Shen J, Wang Z, Ji J, Song H, Wang K, Liu B, Li J, Cui D. Int J Nanomedicine. 2011;6:425-35. doi: 10.2147/IJN.S16498. Epub 2011 Feb 21. PubMed
Faster generation of hiPSCs by coupling high-titer lentivirus and column-based positive selection. Dick E, Matsa E, Young LE, Darling D, Denning C. Nat Protoc. 2011 Jun;6(6):701-14. doi: 10.1038/nprot.2011.320. Epub 2011 May 5. PubMed
Normal collagen and bone production by gene-targeted human osteogenesis imperfecta iPSCs. Deyle DR, Khan IF, Ren G, Wang PR, Kho J, Schwarze U, Russell DW. Mol Ther. 2012 Jan;20(1):204-13. doi: 10.1038/mt.2011.209. Epub 2011 Oct 25. PubMed
SOX2 contributes to melanoma cell invasion. Girouard SD, Laga AC, Mihm MC, Scolyer RA, Thompson JF, Zhan Q, Widlund HR, Lee CW, Murphy GF. Lab Invest. 2012 Mar;92(3):362-70. doi: 10.1038/labinvest.2011.188. Epub 2011 Dec 19. PubMed
Sumoylation of Kruppel-like factor 4 inhibits pluripotency induction but promotes adipocyte differentiation. Tahmasebi S, Ghorbani M, Savage P, Yan K, Gocevski G, Xiao L, You L, Yang XJ. J Biol Chem. 2013 May 3;288(18):12791-804. doi: 10.1074/jbc.M113.465443. Epub 2013 Mar 20. PubMed
SOX2 plays a critical role in EGFR-mediated self-renewal of human prostate cancer stem-like cells. Rybak AP, Tang D. Cell Signal. 2013 Dec;25(12):2734-42. doi: 10.1016/j.cellsig.2013.08.041. Epub 2013 Sep 13. PubMed
CaMKII inhibition rectifies arrhythmic phenotype in a patient-specific model of catecholaminergic polymorphic ventricular tachycardia. Di Pasquale E, Lodola F, Miragoli M, Denegri M, Avelino-Cruz JE, Buonocore M, Nakahama H, Portararo P, Bloise R, Napolitano C, Condorelli G, Priori SG. Cell Death Dis. 2013 Oct 10;4:e843. doi: 10.1038/cddis.2013.369. PubMed
Inhibition of stearoyl-coA desaturase selectively eliminates tumorigenic Nanog-positive cells: improving the safety of iPS cell transplantation to myocardium. Zhang L, Pan Y, Qin G, Chen L, Chatterjee TK, Weintraub NL, Tang Y. Cell Cycle. 2014;13(5):762-71. doi: 10.4161/cc.27677. Epub 2014 Jan 6. PubMed
SOX2 regulates self-renewal and tumorigenicity of human melanoma-initiating cells. Santini R, Pietrobono S, Pandolfi S, Montagnani V, D'Amico M, Penachioni JY, Vinci MC, Borgognoni L, Stecca B. Oncogene. 2014 Sep 18;33(38):4697-708. doi: 10.1038/onc.2014.71. Epub 2014 Mar 31. PubMed
The SUMO conjugating enzyme Ubc9 is required for inducing and maintaining stem cell pluripotency. Tahmasebi S, Ghorbani M, Savage P, Gocevski G, Yang XJ. Stem Cells. 2014 Apr;32(4):1012-20. doi: 10.1002/stem.1600. PubMed
Differentiation of primordial germ cells from induced pluripotent stem cells of primary ovarian insufficiency. Leng L, Tan Y, Gong F, Hu L, Ouyang Q, Zhao Y, Lu G, Lin G. Hum Reprod. 2015 Mar;30(3):737-48. doi: 10.1093/humrep/deu358. Epub 2015 Jan 12. PubMed
iPSC-derived mesenchymal stem cells exert SCF-dependent recovery of cigarette smoke-induced apoptosis/proliferation imbalance in airway cells. Li X, Zhang Y, Liang Y, Cui Y, Yeung SC, Ip MS, Tse HF, Lian Q, Mak JC. J Cell Mol Med. 2016 Sep 19. doi: 10.1111/jcmm.12962. PubMed
Role of FAST Kinase Domains 3 (FASTKD3) in Post-transcriptional Regulation of Mitochondrial Gene Expression. Boehm E, Zornoza M, Jourdain AA, Delmiro Magdalena A, Garcia-Consuegra I, Torres Merino R, Orduna A, Martin MA, Martinou JC, De la Fuente MA, Simarro M. J Biol Chem. 2016 Dec 9;291(50):25877-25887. Epub 2016 Oct 27. PubMed
Derivation of Patient Specific Pluripotent Stem Cells Using Clinically Discarded Cumulus Cells. Chang WF, Hwu YM, Xu J, Lin CJ, Wang SW, Cheng AS, Lu J, Lu CH, Sung LY. PLoS One. 2016 Nov 1;11(11):e0165715. doi: 10.1371/journal.pone.0165715. eCollection 2016. PubMed
Generation of induced pluripotent stem cells (iPSCs) from a retinoblastoma patient carrying a c.2663G>A mutation in RB1 gene. Zeng S, Liu L, Ouyang Q, Zhao Y, Lin G, Hu L, Li W. Stem Cell Res. 2016 Sep;17(2):208-211. doi: 10.1016/j.scr.2016.08.015. Epub 2016 Aug 28. PubMed
No evidence of genome editing activity from Natronobacterium gregoryi Argonaute (NgAgo) in human cells. Javidi-Parsijani P, Niu G, Davis M, Lu P, Atala A, Lu B. PLoS One. 2017 May 11;12(5):e0177444. doi: 10.1371/journal.pone.0177444. eCollection 2017. PubMed
Mesenchymal stem cells alleviate oxidative stress-induced mitochondrial dysfunction in the airways. Li X, Michaeloudes C, Zhang Y, Wiegman CH, Adcock IM, Lian Q, Mak JCW, Bhavsar PK, Chung KF. J Allergy Clin Immunol. 2018 May;141(5):1634-1645.e5. doi: 10.1016/j.jaci.2017.08.017. Epub 2017 Sep 11. PubMed
SOX2-mediated upregulation of CD24 promotes adaptive resistance toward targeted therapy in melanoma. Huser L, Sachindra S, Granados K, Federico A, Larribere L, Novak D, Umansky V, Altevogt P, Utikal J. Int J Cancer. 2018 Dec 15;143(12):3131-3142. doi: 10.1002/ijc.31609. Epub 2018 Oct 16. PubMed
Sox2 promotes tumor aggressiveness and epithelialmesenchymal transition in tongue squamous cell carcinoma. Liu X, Qiao B, Zhao T, Hu F, Lam AK, Tao Q. Int J Mol Med. 2018 Sep;42(3):1418-1426. doi: 10.3892/ijmm.2018.3742. Epub 2018 Jun 26. PubMed
Myocardin-Dependent Kv1.5 Channel Expression Prevents Phenotypic Modulation of Human Vessels in Organ Culture. Arevalo-Martinez M, Cidad P, Garcia-Mateo N, Moreno-Estar S, Serna J, Fernandez M, Sward K, Simarro M, de la Fuente MA, Lopez-Lopez JR, Perez-Garcia MT. Arterioscler Thromb Vasc Biol. 2019 Dec;39(12):e273-e286. doi: 10.1161/ATVBAHA.119.313492. Epub 2019 Oct 10. PubMed
Genes Involved in the Transcriptional Regulation of Pluripotency Are Expressed in Malignant Tumors of the Uterine Cervix and Can Induce Tumorigenic Capacity in a Nontumorigenic Cell Line. Ruiz G, Valencia-Gonzalez HA, Perez-Montiel D, Munoz F, Ocadiz-Delgado R, Fernandez-Retana J, Perez-Plasencia C, Resendis-Antonio O, Gariglio P, Garcia-Carranca A. Stem Cells Int. 2019 Dec 1;2019:7683817. doi: 10.1155/2019/7683817. eCollection 2019. PubMed
SOX2 Expression and Transcriptional Activity Identifies a Subpopulation of Cancer Stem Cells in Sarcoma with Prognostic Implications. Menendez ST, Rey V, Martinez-Cruzado L, Gonzalez MV, Morales-Molina A, Santos L, Blanco V, Alvarez C, Estupinan O, Allonca E, Rodrigo JP, Garcia-Castro J, Garcia-Pedrero JM, Rodriguez R. Cancers (Basel). 2020 Apr 13;12(4). pii: cancers12040964. doi: 10.3390/cancers12040964. PubMed
Generation of hepatocyte-like cells from human urinary epithelial cells and the role of autophagy during direct reprogramming. Wu H, Du C, Yang F, Zheng X, Qiu D, Zhang Q, Chen W, Xu Y. Biochem Biophys Res Commun. 2020 Jun 30;527(3):723-729. doi: 10.1016/j.bbrc.2020.03.119. Epub 2020 May 18. PubMed
CAMK2A supported tumor initiating cells of lung adenocarcinoma by upregulating SOX2 through EZH2 phosphorylation. Wang SQ, Liu J, Qin J, Zhu Y, Tin VP, Yam JWP, Wong MP, Xiao ZJ. Cell Death Dis. 2020 Jun 1;11(6):410. doi: 10.1038/s41419-020-2553-6. PubMed
Coronavirus disease 2019 vaccine response in pregnant and lactating women: a cohort study. Gray KJ, Bordt EA, Atyeo C, Deriso E, Akinwunmi B, Young N, Baez AM, Shook LL, Cvrk D, James K, De Guzman R, Brigida S, Diouf K, Goldfarb I, Bebell LM, Yonker LM, Fasano A, Rabi SA, Elovitz MA, Alter G, Edlow AG. Am J Obstet Gynecol. 2021 Sep;225(3):303.e1-303.e17. doi: 10.1016/j.ajog.2021.03.023. Epub 2021 Mar 26. PubMed
Identification and Characterization of Cancer Stem-Like Cells in ALK-Positive Anaplastic Large Cell Lymphoma Using the SORE6 Reporter. Li J, Haque M, Shang C, Hassan B, Liu D, Chen W, Lai R. Curr Issues Mol Biol. 2021 Jul 2;43(2):543-557. doi: 10.3390/cimb43020041. PubMed
High Frequency of Tumor Propagating Cells in Fusion-Positive Rhabdomyosarcoma. Generali M, Satheesha S, Bode PK, Wanner D, Schafer BW, Casanova EA. Genes (Basel). 2021 Aug 31;12(9). pii: genes12091373. doi: 10.3390/genes12091373. PubMed
Protease inhibitor Camostat Mesyalte blocks wild type SARS-CoV-2 and D614G viral entry in human engineered miniature lungs. Wu T, Rabi SA, Michaud WA, Becerra D, Gilpin SE, Mino-Kenudson M, Ott HC. Biomaterials. 2022 Jun;285:121509. doi: 10.1016/j.biomaterials.2022.121509. Epub 2022 Apr 11. PubMed

If you have published an article using this plasmid, please email us at [email protected] to have your article added to this page.