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pCMV-T7-ABE8e-nSpRY-P2A-EGFP (KAC1069) Citations (2)

Originally described in: Optimization of base editors for the functional correction of SMN2 as a treatment for spinal muscular atrophy.
Alves CRR, Ha LL, Yaworski R, Sutton ER, Lazzarotto CR, Christie KA, Reilly A, Beauvais A, Doll RM, de la Cruz D, Maguire CA, Swoboda KJ, Tsai SQ, Kothary R, Kleinstiver BP Nat Biomed Eng. 2023 Dec 6. doi: 10.1038/s41551-023-01132-z.
PubMed Journal

Articles Citing pCMV-T7-ABE8e-nSpRY-P2A-EGFP (KAC1069)

Articles
Dissecting the epigenetic regulation of the fetal hemoglobin genes to unravel a novel therapeutic approach for beta-hemoglobinopathies. Amistadi S, Fontana L, Magnoni C, Felix T, Charvin MK, Martinucci P, Gautier C, Greau L, Bessieres B, Antoniou P, Romano O, Allemand E, Mussolino C, Miccio A. Nucleic Acids Res. 2025 Jul 8;53(13):gkaf637. doi: 10.1093/nar/gkaf637. PubMed
ABE9 fused to SpRY Cas9 nickase enables precise generation of bystander free mouse models. Ong JK, Bhunia S, Hilbert B, Kirschner V, Duglosz S, Zimmermann F, Freichel M, Cornean A. Sci Rep. 2026 Feb 20;16(1):7463. doi: 10.1038/s41598-026-40642-z. PubMed

Associated Plasmids

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