pcDNA3-myc-CUL3 Citations (20)
Originally described in: ROC1, a homolog of APC11, represents a family of cullin partners with an associated ubiquitin ligase activity.Ohta T, Michel JJ, Schottelius AJ, Xiong Y Mol Cell. 1999 Apr . 3(4):535-41. PubMed Journal
Articles Citing pcDNA3-myc-CUL3
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| A homozygous mutation in KCTD7 links neuronal ceroid lipofuscinosis to the ubiquitin-proteasome system. Staropoli JF, Karaa A, Lim ET, Kirby A, Elbalalesy N, Romansky SG, Leydiker KB, Coppel SH, Barone R, Xin W, MacDonald ME, Abdenur JE, Daly MJ, Sims KB, Cotman SL. Am J Hum Genet. 2012 Jul 13;91(1):202-8. doi: 10.1016/j.ajhg.2012.05.023. Epub 2012 Jun 28. PubMed |
| Giant axonal neuropathy-associated gigaxonin mutations impair intermediate filament protein degradation. Mahammad S, Murthy SN, Didonna A, Grin B, Israeli E, Perrot R, Bomont P, Julien JP, Kuczmarski E, Opal P, Goldman RD. J Clin Invest. 2013 May;123(5):1964-75. doi: 10.1172/JCI66387. Epub 2013 Apr 15. PubMed |
| Kbtbd5 is regulated by MyoD and restricted to the myogenic lineage. Bowlin KM, Embree LJ, Garry MG, Garry DJ, Shi X. Differentiation. 2013 Nov-Dec;86(4-5):184-91. doi: 10.1016/j.diff.2013.08.002. Epub 2013 Dec 20. PubMed |
| Evidence for ubiquitin-regulated nuclear and subnuclear trafficking among Paramyxovirinae matrix proteins. Pentecost M, Vashisht AA, Lester T, Voros T, Beaty SM, Park A, Wang YE, Yun TE, Freiberg AN, Wohlschlegel JA, Lee B. PLoS Pathog. 2015 Mar 17;11(3):e1004739. doi: 10.1371/journal.ppat.1004739. eCollection 2015 Mar. PubMed |
| CRL3IBTK Regulates the Tumor Suppressor Pdcd4 through Ubiquitylation Coupled to Proteasomal Degradation. Pisano A, Ceglia S, Palmieri C, Vecchio E, Fiume G, de Laurentiis A, Mimmi S, Falcone C, Iaccino E, Scialdone A, Pontoriero M, Masci FF, Valea R, Krishnan S, Gaspari M, Cuda G, Scala G, Quinto I. J Biol Chem. 2015 May 29;290(22):13958-71. doi: 10.1074/jbc.M114.634535. Epub 2015 Apr 16. PubMed |
| Kelch Repeat and BTB Domain Containing Protein 5 (Kbtbd5) Regulates Skeletal Muscle Myogenesis through the E2F1-DP1 Complex. Gong W, Gohla RM, Bowlin KM, Koyano-Nakagawa N, Garry DJ, Shi X. J Biol Chem. 2015 Jun 12;290(24):15350-61. doi: 10.1074/jbc.M114.629956. Epub 2015 May 4. PubMed |
| The Cullin 4A/B-DDB1-Cereblon E3 Ubiquitin Ligase Complex Mediates the Degradation of CLC-1 Chloride Channels. Chen YA, Peng YJ, Hu MC, Huang JJ, Chien YC, Wu JT, Chen TY, Tang CY. Sci Rep. 2015 May 29;5:10667. doi: 10.1038/srep10667. PubMed |
| Protein Kinase R Degradation Is Essential for Rift Valley Fever Virus Infection and Is Regulated by SKP1-CUL1-F-box (SCF)FBXW11-NSs E3 Ligase. Mudhasani R, Tran JP, Retterer C, Kota KP, Whitehouse CA, Bavari S. PLoS Pathog. 2016 Feb 2;12(2):e1005437. doi: 10.1371/journal.ppat.1005437. eCollection 2016 Feb. PubMed |
| Comparative Proteomics Reveals Strain-Specific beta-TrCP Degradation via Rotavirus NSP1 Hijacking a Host Cullin-3-Rbx1 Complex. Ding S, Mooney N, Li B, Kelly MR, Feng N, Loktev AV, Sen A, Patton JT, Jackson PK, Greenberg HB. PLoS Pathog. 2016 Oct 5;12(10):e1005929. doi: 10.1371/journal.ppat.1005929. eCollection 2016 Oct. PubMed |
| Cullin 7 mediates proteasomal and lysosomal degradations of rat Eag1 potassium channels. Hsu PH, Ma YT, Fang YC, Huang JJ, Gan YL, Chang PT, Jow GM, Tang CY, Jeng CJ. Sci Rep. 2017 Jan 18;7:40825. doi: 10.1038/srep40825. PubMed |
| UBE2M Is a Stress-Inducible Dual E2 for Neddylation and Ubiquitylation that Promotes Targeted Degradation of UBE2F. Zhou W, Xu J, Tan M, Li H, Li H, Wei W, Sun Y. Mol Cell. 2018 Jun 21;70(6):1008-1024.e6. doi: 10.1016/j.molcel.2018.06.002. PubMed |
Cancer Mutations of the Tumor Suppressor SPOP Disrupt the Formation of Active, Phase-Separated Compartments.
Bouchard JJ, Otero JH, Scott DC, Szulc E, Martin EW, Sabri N, Granata D, Marzahn MR, Lindorff-Larsen K, Salvatella X, Schulman BA, Mittag T.
Mol Cell. 2018 Oct 4;72(1):19-36.e8. doi: 10.1016/j.molcel.2018.08.027. Epub 2018 Sep 20.
PubMed
Associated Plasmids |
| TRIM28 protects TRIM24 from SPOP-mediated degradation and promotes prostate cancer progression. Fong KW, Zhao JC, Song B, Zheng B, Yu J. Nat Commun. 2018 Nov 27;9(1):5007. doi: 10.1038/s41467-018-07475-5. PubMed |
| Vaccinia Virus BBK E3 Ligase Adaptor A55 Targets Importin-Dependent NF-kappaB Activation and Inhibits CD8(+) T-Cell Memory. Pallett MA, Ren H, Zhang RY, Scutts SR, Gonzalez L, Zhu Z, Maluquer de Motes C, Smith GL. J Virol. 2019 May 1;93(10). pii: JVI.00051-19. doi: 10.1128/JVI.00051-19. Print 2019 May 15. PubMed |
| Molecular basis of cullin-3 (Cul3) ubiquitin ligase subversion by vaccinia virus protein A55. Gao C, Pallett MA, Croll TI, Smith GL, Graham SC. J Biol Chem. 2019 Apr 19;294(16):6416-6429. doi: 10.1074/jbc.RA118.006561. Epub 2019 Feb 28. PubMed |
| Label-Free Interactome Analysis Revealed an Essential Role of CUL3-KEAP1 Complex in Mediating the Ubiquitination and Degradation of PHD2. Luo A, Chen Y. J Proteome Res. 2020 Jan 3;19(1):260-268. doi: 10.1021/acs.jproteome.9b00513. Epub 2019 Dec 6. PubMed |
| Synaptic control of DNA methylation involves activity-dependent degradation of DNMT3A1 in the nucleus. Bayraktar G, Yuanxiang P, Confettura AD, Gomes GM, Raza SA, Stork O, Tajima S, Suetake I, Karpova A, Yildirim F, Kreutz MR. Neuropsychopharmacology. 2020 Nov;45(12):2120-2130. doi: 10.1038/s41386-020-0780-2. Epub 2020 Jul 29. PubMed |
| Intrinsically disordered substrates dictate SPOP subnuclear localization and ubiquitination activity. Usher ET, Sabri N, Rohac R, Boal AK, Mittag T, Showalter SA. J Biol Chem. 2021 Jan-Jun;296:100693. doi: 10.1016/j.jbc.2021.100693. Epub 2021 Apr 22. PubMed |
| Proteolysis of gamma-tubulin small complex proteins is mediated by the ubiquitin-proteasome system. Yin C, Lui ESW, Jiang T, Qi RZ. FEBS Lett. 2021 Aug;595(15):1987-1996. doi: 10.1002/1873-3468.14146. Epub 2021 Jun 23. PubMed |
| Higher-order SPOP assembly reveals a basis for cancer mutant dysregulation. Cuneo MJ, O'Flynn BG, Lo YH, Sabri N, Mittag T. Mol Cell. 2023 Mar 2;83(5):731-745.e4. doi: 10.1016/j.molcel.2022.12.033. Epub 2023 Jan 23. PubMed |
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