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pcDNA3-HA2-ROC1 Citations (10)

Originally described in: ROC1, a homolog of APC11, represents a family of cullin partners with an associated ubiquitin ligase activity.
Ohta T, Michel JJ, Schottelius AJ, Xiong Y Mol Cell. 1999 Apr . 3(4):535-41.
PubMed Journal

Articles Citing pcDNA3-HA2-ROC1

Articles
CRL3IBTK Regulates the Tumor Suppressor Pdcd4 through Ubiquitylation Coupled to Proteasomal Degradation. Pisano A, Ceglia S, Palmieri C, Vecchio E, Fiume G, de Laurentiis A, Mimmi S, Falcone C, Iaccino E, Scialdone A, Pontoriero M, Masci FF, Valea R, Krishnan S, Gaspari M, Cuda G, Scala G, Quinto I. J Biol Chem. 2015 May 29;290(22):13958-71. doi: 10.1074/jbc.M114.634535. Epub 2015 Apr 16. PubMed
Kelch Repeat and BTB Domain Containing Protein 5 (Kbtbd5) Regulates Skeletal Muscle Myogenesis through the E2F1-DP1 Complex. Gong W, Gohla RM, Bowlin KM, Koyano-Nakagawa N, Garry DJ, Shi X. J Biol Chem. 2015 Jun 12;290(24):15350-61. doi: 10.1074/jbc.M114.629956. Epub 2015 May 4. PubMed
Mitochondrial Stasis Reveals p62-Mediated Ubiquitination in Parkin-Independent Mitophagy and Mitigates Nonalcoholic Fatty Liver Disease. Yamada T, Murata D, Adachi Y, Itoh K, Kameoka S, Igarashi A, Kato T, Araki Y, Huganir RL, Dawson TM, Yanagawa T, Okamoto K, Iijima M, Sesaki H. Cell Metab. 2018 Oct 2;28(4):588-604.e5. doi: 10.1016/j.cmet.2018.06.014. Epub 2018 Jul 12. PubMed
Protein kinase CK2 activation is required for transforming growth factor beta-induced epithelial-mesenchymal transition. Kim S, Ham S, Yang K, Kim K. Mol Oncol. 2018 Oct;12(10):1811-1826. doi: 10.1002/1878-0261.12378. Epub 2018 Sep 21. PubMed
Cancer Mutations of the Tumor Suppressor SPOP Disrupt the Formation of Active, Phase-Separated Compartments. Bouchard JJ, Otero JH, Scott DC, Szulc E, Martin EW, Sabri N, Granata D, Marzahn MR, Lindorff-Larsen K, Salvatella X, Schulman BA, Mittag T. Mol Cell. 2018 Oct 4;72(1):19-36.e8. doi: 10.1016/j.molcel.2018.08.027. Epub 2018 Sep 20. PubMed

Associated Plasmids

Curcumin induces stabilization of Nrf2 protein through Keap1 cysteine modification. Shin JW, Chun KS, Kim DH, Kim SJ, Kim SH, Cho NC, Na HK, Surh YJ. Biochem Pharmacol. 2020 Mar;173:113820. doi: 10.1016/j.bcp.2020.113820. Epub 2020 Jan 20. PubMed
KDM2B Overexpression Facilitates Lytic De Novo KSHV Infection by Inducing AP-1 Activity Through Interaction with the SCF E3 Ubiquitin Ligase Complex. Naik NG, Lee SC, Alonso JD, Toth Z. J Virol. 2021 Mar 10. pii: JVI.00331-21. doi: 10.1128/JVI.00331-21. PubMed
Intrinsically disordered substrates dictate SPOP subnuclear localization and ubiquitination activity. Usher ET, Sabri N, Rohac R, Boal AK, Mittag T, Showalter SA. J Biol Chem. 2021 Jan-Jun;296:100693. doi: 10.1016/j.jbc.2021.100693. Epub 2021 Apr 22. PubMed
Higher-order SPOP assembly reveals a basis for cancer mutant dysregulation. Cuneo MJ, O'Flynn BG, Lo YH, Sabri N, Mittag T. Mol Cell. 2023 Mar 2;83(5):731-745.e4. doi: 10.1016/j.molcel.2022.12.033. Epub 2023 Jan 23. PubMed
Reduction of oligomer size modulates the competition between cluster formation and phase separation of the tumor suppressor SPOP. Sabri N, Cuneo MJ, Marzahn MR, Lee J, Bouchard JJ, Gullulu O, Vaithiyalingam S, Borgia MB, Schmit J, Mittag T. J Biol Chem. 2023 Dec;299(12):105427. doi: 10.1016/j.jbc.2023.105427. Epub 2023 Nov 4. PubMed

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