pEGFP-C1-Ataxin3Q28 Citations (15)

Originally described in: Live-cell imaging reveals divergent intracellular dynamics of polyglutamine disease proteins and supports a sequestration model of pathogenesis.
Chai Y, Shao J, Miller VM, Williams A, Paulson HL Proc Natl Acad Sci U S A. 2002 Jul 9. 99(14):9310-5. PubMed Journal

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Articles Citing pEGFP-C1-Ataxin3Q28

Articles
Insulin/IGF-1 signaling regulates proteasome activity through the deubiquitinating enzyme UBH-4. Matilainen O, Arpalahti L, Rantanen V, Hautaniemi S, Holmberg CI. Cell Rep. 2013 Jun 27;3(6):1980-95. doi: 10.1016/j.celrep.2013.05.012. Epub 2013 Jun 13. PubMed
Mahogunin ring finger 1 suppresses misfolded polyglutamine aggregation and cytotoxicity. Chhangani D, Nukina N, Kurosawa M, Amanullah A, Joshi V, Upadhyay A, Mishra A. Biochim Biophys Acta. 2014 Sep;1842(9):1472-84. doi: 10.1016/j.bbadis.2014.04.014. Epub 2014 Apr 24. PubMed
Ubiquitin ligase ITCH recruitment suppresses the aggregation and cellular toxicity of cytoplasmic misfolded proteins. Chhangani D, Upadhyay A, Amanullah A, Joshi V, Mishra A. Sci Rep. 2014 May 28;4:5077. doi: 10.1038/srep05077. PubMed
Inactivation of PNKP by mutant ATXN3 triggers apoptosis by activating the DNA damage-response pathway in SCA3. Gao R, Liu Y, Silva-Fernandes A, Fang X, Paulucci-Holthauzen A, Chatterjee A, Zhang HL, Matsuura T, Choudhary S, Ashizawa T, Koeppen AH, Maciel P, Hazra TK, Sarkar PS. PLoS Genet. 2015 Jan 15;11(1):e1004834. doi: 10.1371/journal.pgen.1004834. eCollection 2015 Jan. PubMed
Cytosolic PTEN-induced Putative Kinase 1 Is Stabilized by the NF-kappaB Pathway and Promotes Non-selective Mitophagy. Lim GG, Chua DS, Basil AH, Chan HY, Chai C, Arumugam T, Lim KL. J Biol Chem. 2015 Jul 3;290(27):16882-93. doi: 10.1074/jbc.M114.622399. Epub 2015 May 18. PubMed
Loss of laforin or malin results in increased Drp1 level and concomitant mitochondrial fragmentation in Lafora disease mouse models. Upadhyay M, Agarwal S, Bhadauriya P, Ganesh S. Neurobiol Dis. 2017 Jan 4;100:39-51. doi: 10.1016/j.nbd.2017.01.002. PubMed
Lanosterol Suppresses the Aggregation and Cytotoxicity of Misfolded Proteins Linked with Neurodegenerative Diseases. Upadhyay A, Amanullah A, Mishra R, Kumar A, Mishra A. Mol Neurobiol. 2017 Jan 19. doi: 10.1007/s12035-016-0377-2. PubMed
Polyglutamine tracts regulate beclin 1-dependent autophagy. Ashkenazi A, Bento CF, Ricketts T, Vicinanza M, Siddiqi F, Pavel M, Squitieri F, Hardenberg MC, Imarisio S, Menzies FM, Rubinsztein DC. Nature. 2017 May 4;545(7652):108-111. doi: 10.1038/nature22078. Epub 2017 Apr 26. PubMed
PTENalpha regulates mitophagy and maintains mitochondrial quality control. Li G, Yang J, Yang C, Zhu M, Jin Y, McNutt MA, Yin Y. Autophagy. 2018;14(10):1742-1760. doi: 10.1080/15548627.2018.1489477. Epub 2018 Aug 1. PubMed
Polyphenolic flavonoid (Myricetin) upregulated proteasomal degradation mechanisms: Eliminates neurodegenerative proteins aggregation. Joshi V, Mishra R, Upadhyay A, Amanullah A, Poluri KM, Singh S, Kumar A, Mishra A. J Cell Physiol. 2019 Nov;234(11):20900-20914. doi: 10.1002/jcp.28695. Epub 2019 Apr 19. PubMed
Rationally designed small molecules targeting toxic CAG repeat RNA that causes Huntington's disease (HD) and spinocerebellar ataxia (SCAs). Khan E, Biswas S, Mishra SK, Mishra R, Samanta S, Mishra A, Tawani A, Kumar A. Biochimie. 2019 Aug;163:21-32. doi: 10.1016/j.biochi.2019.05.001. Epub 2019 May 8. PubMed
Discovery of a potent small molecule inhibiting Huntington's disease (HD) pathogenesis via targeting CAG repeats RNA and Poly Q protein. Khan E, Mishra SK, Mishra R, Mishra A, Kumar A. Sci Rep. 2019 Nov 14;9(1):16872. doi: 10.1038/s41598-019-53410-z. PubMed
DNAzyme Cleavage of CAG Repeat RNA in Polyglutamine Diseases. Zhang N, Bewick B, Schultz J, Tiwari A, Krencik R, Zhang A, Adachi K, Xia G, Yun K, Sarkar P, Ashizawa T. Neurotherapeutics. 2021 Jun 23. pii: 10.1007/s13311-021-01075-w. doi: 10.1007/s13311-021-01075-w. PubMed
The stress granule protein G3BP1 alleviates spinocerebellar ataxia-associated deficits. Koppenol R, Conceicao A, Afonso IT, Afonso-Reis R, Costa RG, Tome S, Teixeira D, da Silva JP, Codesso JM, Brito DVC, Mendonca L, Marcelo A, Pereira de Almeida L, Matos CA, Nobrega C. Brain. 2022 Dec 13:awac473. doi: 10.1093/brain/awac473. PubMed
Itraconazole Confers Cytoprotection Against Neurodegenerative Disease-Associated Abnormal Protein Aggregation. Dubey AR, Mishra R, Jagtap YA, Kinger S, Kumar P, Dhiman R, Ghosh S, Singh S, Prasad A, Jana NR, Mishra A. Mol Neurobiol. 2023 May;60(5):2397-2412. doi: 10.1007/s12035-023-03230-0. Epub 2023 Jan 19. PubMed

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