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pLM-mCherry-Klf4 Citations (9)

Originally described in: Stoichiometric and temporal requirements of Oct4, Sox2, Klf4, and c-Myc expression for efficient human iPSC induction and differentiation.
Papapetrou EP, Tomishima MJ, Chambers SM, Mica Y, Reed E, Menon J, Tabar V, Mo Q, Studer L, Sadelain M Proc Natl Acad Sci U S A. 2009 Aug 4. 106(31):12759-64.
PubMed Journal

Articles Citing pLM-mCherry-Klf4

Activation of AMP-activated protein kinase (AMPK) provides a metabolic barrier to reprogramming somatic cells into stem cells. Vazquez-Martin A, Vellon L, Quiros PM, Cufi S, Ruiz de Galarreta E, Oliveras-Ferraros C, Martin AG, Martin-Castillo B, Lopez-Otin C, Menendez JA. Cell Cycle. 2012 Mar 1;11(5):974-89. doi: 10.4161/cc.11.5.19450. Epub 2012 Mar 1. PubMed
KLF4 N-terminal variance modulates induced reprogramming to pluripotency. Kim SI, Oceguera-Yanez F, Hirohata R, Linker S, Okita K, Yamada Y, Yamamoto T, Yamanaka S, Woltjen K. Stem Cell Reports. 2015 Apr 14;4(4):727-43. doi: 10.1016/j.stemcr.2015.02.004. Epub 2015 Mar 12. PubMed

Associated Plasmids

Targeted disruption of DNMT1, DNMT3A and DNMT3B in human embryonic stem cells. Liao J, Karnik R, Gu H, Ziller MJ, Clement K, Tsankov AM, Akopian V, Gifford CA, Donaghey J, Galonska C, Pop R, Reyon D, Tsai SQ, Mallard W, Joung JK, Rinn JL, Gnirke A, Meissner A. Nat Genet. 2015 May;47(5):469-78. doi: 10.1038/ng.3258. Epub 2015 Mar 30. PubMed
Aven recognition of RNA G-quadruplexes regulates translation of the mixed lineage leukemia protooncogenes. Thandapani P, Song J, Gandin V, Cai Y, Rouleau SG, Garant JM, Boisvert FM, Yu Z, Perreault JP, Topisirovic I, Richard S. Elife. 2015 Aug 12;4. doi: 10.7554/eLife.06234. PubMed
KLF4 is downregulated but not mutated during human esophageal squamous cell carcinogenesis and has tumor stage-specific functions. Yang Y, Katz JP. Cancer Biol Ther. 2016 Apr 2;17(4):422-9. doi: 10.1080/15384047.2016.1156260. Epub 2016 Mar 2. PubMed
A Core Regulatory Circuit in Glioblastoma Stem Cells Links MAPK Activation to a Transcriptional Program of Neural Stem Cell Identity. Riddick G, Kotliarova S, Rodriguez V, Kim HS, Linkous A, Storaska AJ, Ahn S, Walling J, Belova G, Fine HA. Sci Rep. 2017 Mar 3;7:43605. doi: 10.1038/srep43605. PubMed
Lentiviral vector expression of Klf4 enhances chondrogenesis and reduces hypertrophy in equine chondrocytes. Gurusinghe S, Bandara N, Hilbert B, Trope G, Wang L, Strappe P. Gene. 2019 Jan 5;680:9-19. doi: 10.1016/j.gene.2018.09.013. Epub 2018 Sep 8. PubMed
A Novel Function for KLF4 in Modulating the De-differentiation of EpCAM(-)/CD133(-) nonStem Cells into EpCAM(+)/CD133(+) Liver Cancer Stem Cells in HCC Cell Line HuH7. Karagonlar ZF, Akbari S, Karabicici M, Sahin E, Avci ST, Ersoy N, Ates KE, Balli T, Karacicek B, Kaplan KN, Celiker C, Atabey N, Erdal E. Cells. 2020 May 12;9(5). pii: cells9051198. doi: 10.3390/cells9051198. PubMed
KLF4 is a therapeutically tractable brake on fibroblast activation that promotes resolution of pulmonary fibrosis. Penke LR, Speth JM, Huang SK, Fortier SM, Baas J, Peters-Golden M. JCI Insight. 2022 Aug 22;7(16):e160688. doi: 10.1172/jci.insight.160688. PubMed

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