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pDONR223-PDGFRA Citations (8)

Originally described in: COT drives resistance to RAF inhibition through MAP kinase pathway reactivation.
Johannessen CM, Boehm JS, Kim SY, Thomas SR, Wardwell L, Johnson LA, Emery CM, Stransky N, Cogdill AP, Barretina J, Caponigro G, Hieronymus H, Murray RR, Salehi-Ashtiani K, Hill DE, Vidal M, Zhao JJ, Yang X, Alkan O, Kim S, Harris JL, Wilson CJ, Myer VE, Finan PM, Root DE, Roberts TM, Golub T, Flaherty KT, Dummer R, Weber BL, Sellers WR, Schlegel R, Wargo JA, Hahn WC, Garraway LA Nature. 2010 Nov 24. ():.
PubMed Journal

Articles Citing pDONR223-PDGFRA

Adaptive Chromatin Remodeling Drives Glioblastoma Stem Cell Plasticity and Drug Tolerance. Liau BB, Sievers C, Donohue LK, Gillespie SM, Flavahan WA, Miller TE, Venteicher AS, Hebert CH, Carey CD, Rodig SJ, Shareef SJ, Najm FJ, van Galen P, Wakimoto H, Cahill DP, Rich JN, Aster JC, Suva ML, Patel AP, Bernstein BE. Cell Stem Cell. 2016 Dec 2. pii: S1934-5909(16)30399-X. doi: 10.1016/j.stem.2016.11.003. PubMed
Proteolytic cleavages in the extracellular domain of receptor tyrosine kinases by membrane-associated serine proteases. Chen LM, Chai KX. Oncotarget. 2017 Apr 10;8(34):56490-56505. doi: 10.18632/oncotarget.17009. eCollection 2017 Aug 22. PubMed
PDGFRalpha/PDGFRbeta signaling balance modulates progenitor cell differentiation into white and beige adipocytes. Gao Z, Daquinag AC, Su F, Snyder B, Kolonin MG. Development. 2018 Jan 4;145(1). pii: dev.155861. doi: 10.1242/dev.155861. PubMed
Synectin promotes fibrogenesis by regulating PDGFR isoforms through distinct mechanisms. Drinane MC, Yaqoob U, Yu H, Luo F, Greuter T, Arab JP, Kostallari E, Verma VK, Maiers J, De Assuncao TM, Simons M, Mukhopadhyay D, Kisseleva T, Brenner DA, Urrutia R, Lomberk G, Gao Y, Ligresti G, Tschumperlin DJ, Revzin A, Cao S, Shah VH. JCI Insight. 2017 Dec 21;2(24). pii: 92821. doi: 10.1172/jci.insight.92821. PubMed
Modeling Human Cytomegalovirus-Induced Microcephaly in Human iPSC-Derived Brain Organoids. Sun G, Chiuppesi F, Chen X, Wang C, Tian E, Nguyen J, Kha M, Trinh D, Zhang H, Marchetto MC, Song H, Ming GL, Gage FH, Diamond DJ, Wussow F, Shi Y. Cell Rep Med. 2020 Mar 25;1(1):100002. doi: 10.1016/j.xcrm.2020.100002. eCollection 2020 Apr 21. PubMed
An oncogenic splice variant of PDGFRalpha in adult glioblastoma as a therapeutic target for selective CDK4/6 inhibitors. Hamada T, Akahane T, Yokoyama S, Higa N, Kirishima M, Matsuo K, Shimokawa M, Yoshimoto K, Tanimoto A. Sci Rep. 2022 Jan 24;12(1):1275. doi: 10.1038/s41598-022-05391-9. PubMed
Physical and functional interactome atlas of human receptor tyrosine kinases. Salokas K, Liu X, Ohman T, Chowdhury I, Gawriyski L, Keskitalo S, Varjosalo M. EMBO Rep. 2022 Apr 5:e54041. doi: 10.15252/embr.202154041. PubMed

Associated Plasmids

PDGFR dimer-specific activation, trafficking and downstream signaling dynamics. Rogers MA, Campana MB, Long R, Fantauzzo KA. J Cell Sci. 2022 Sep 1;135(17):jcs259686. doi: 10.1242/jcs.259686. Epub 2022 Sep 7. PubMed

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