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pDONR223-PDGFRB Citations (8)

Originally described in: COT drives resistance to RAF inhibition through MAP kinase pathway reactivation.
Johannessen CM, Boehm JS, Kim SY, Thomas SR, Wardwell L, Johnson LA, Emery CM, Stransky N, Cogdill AP, Barretina J, Caponigro G, Hieronymus H, Murray RR, Salehi-Ashtiani K, Hill DE, Vidal M, Zhao JJ, Yang X, Alkan O, Kim S, Harris JL, Wilson CJ, Myer VE, Finan PM, Root DE, Roberts TM, Golub T, Flaherty KT, Dummer R, Weber BL, Sellers WR, Schlegel R, Wargo JA, Hahn WC, Garraway LA Nature. 2010 Dec 16;468(7326):968-72. doi: 10.1038/nature09627
PubMed Journal

Articles Citing pDONR223-PDGFRB

Mutant p53 drives pancreatic cancer metastasis through cell-autonomous PDGF receptor beta signaling. Weissmueller S, Manchado E, Saborowski M, Morris JP 4th, Wagenblast E, Davis CA, Moon SH, Pfister NT, Tschaharganeh DF, Kitzing T, Aust D, Markert EK, Wu J, Grimmond SM, Pilarsky C, Prives C, Biankin AV, Lowe SW. Cell. 2014 Apr 10;157(2):382-94. doi: 10.1016/j.cell.2014.01.066. PubMed
Regulation of endogenous transmembrane receptors through optogenetic Cry2 clustering. Bugaj LJ, Spelke DP, Mesuda CK, Varedi M, Kane RS, Schaffer DV. Nat Commun. 2015 Apr 22;6:6898. doi: 10.1038/ncomms7898. PubMed
JNK Pathway Activation Modulates Acquired Resistance to EGFR/HER2-Targeted Therapies. Manole S, Richards EJ, Meyer AS. Cancer Res. 2016 Sep 15;76(18):5219-28. doi: 10.1158/0008-5472.CAN-16-0123. Epub 2016 Jul 22. PubMed
Proteolytic cleavages in the extracellular domain of receptor tyrosine kinases by membrane-associated serine proteases. Chen LM, Chai KX. Oncotarget. 2017 Apr 10;8(34):56490-56505. doi: 10.18632/oncotarget.17009. eCollection 2017 Aug 22. PubMed
Copper Chelation Inhibits BRAF(V600E)-Driven Melanomagenesis and Counters Resistance to BRAF(V600E) and MEK1/2 Inhibitors. Brady DC, Crowe MS, Greenberg DN, Counter CM. Cancer Res. 2017 Nov 15;77(22):6240-6252. doi: 10.1158/0008-5472.CAN-16-1190. Epub 2017 Oct 6. PubMed
PDGFRalpha/PDGFRbeta signaling balance modulates progenitor cell differentiation into white and beige adipocytes. Gao Z, Daquinag AC, Su F, Snyder B, Kolonin MG. Development. 2018 Jan 4;145(1). pii: dev.155861. doi: 10.1242/dev.155861. PubMed
Synectin promotes fibrogenesis by regulating PDGFR isoforms through distinct mechanisms. Drinane MC, Yaqoob U, Yu H, Luo F, Greuter T, Arab JP, Kostallari E, Verma VK, Maiers J, De Assuncao TM, Simons M, Mukhopadhyay D, Kisseleva T, Brenner DA, Urrutia R, Lomberk G, Gao Y, Ligresti G, Tschumperlin DJ, Revzin A, Cao S, Shah VH. JCI Insight. 2017 Dec 21;2(24). pii: 92821. doi: 10.1172/jci.insight.92821. PubMed
PDGFR dimer-specific activation, trafficking and downstream signaling dynamics. Rogers MA, Campana MB, Long R, Fantauzzo KA. J Cell Sci. 2022 Sep 1;135(17):jcs259686. doi: 10.1242/jcs.259686. Epub 2022 Sep 7. PubMed

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