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HIR WT Citations (6)

Originally described in: Insulin receptor tyrosine kinase activity and phosphorylation of tyrosines 1162 and 1163 are required for insulin-increased prolactin gene expression.
Jacob KK, Whittaker J, Stanley FM Mol Cell Endocrinol. 2002 Jan 15. 186(1):7-16.
PubMed Journal

Articles Citing HIR WT

Production of recombinant human proinsulin in the milk of transgenic mice. Qian X, Kraft J, Ni Y, Zhao FQ. Sci Rep. 2014 Sep 30;4:6465. doi: 10.1038/srep06465. PubMed
PRAS40 deregulates apoptosis in Ewing sarcoma family tumors by enhancing the insulin receptor/Akt and mTOR signaling pathways. Lv D, Liu J, Guo L, Wu D, Matsumoto K, Huang L. Am J Cancer Res. 2016 Jan 15;6(2):486-97. eCollection 2016. PubMed
Insulin differentially affects the distribution kinetics of amyloid beta 40 and 42 in plasma and brain. Swaminathan SK, Ahlschwede KM, Sarma V, Curran GL, Omtri RS, Decklever T, Lowe VJ, Poduslo JF, Kandimalla KK. J Cereb Blood Flow Metab. 2018 May;38(5):904-918. doi: 10.1177/0271678X17709709. Epub 2017 Jun 1. PubMed
Proteolytic cleavages in the extracellular domain of receptor tyrosine kinases by membrane-associated serine proteases. Chen LM, Chai KX. Oncotarget. 2017 Apr 10;8(34):56490-56505. doi: 10.18632/oncotarget.17009. eCollection 2017 Aug 22. PubMed
Antitumor effects of beta-elemene via targeting the phosphorylation of insulin receptor. Wu D, Lv D, Zhang T, Guo L, Ma F, Zhang C, Lv G, Huang L. Endocr Relat Cancer. 2018 Nov 1. pii: ERC-18-0370.R2. doi: 10.1530/ERC-18-0370. PubMed
Misfolded proinsulin impairs processing of precursor of insulin receptor and insulin signaling in beta cells. Liu S, Li X, Yang J, Zhu R, Fan Z, Xu X, Feng W, Cui J, Sun J, Liu M. FASEB J. 2019 Oct;33(10):11338-11348. doi: 10.1096/fj.201900442R. Epub 2019 Aug 1. PubMed

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