pCMV-flag YAP2 5SA Citations (44)

Originally described in: Inactivation of YAP oncoprotein by the Hippo pathway is involved in cell contact inhibition and tissue growth control.
Zhao B, Wei X, Li W, Udan RS, Yang Q, Kim J, Xie J, Ikenoue T, Yu J, Li L, Zheng P, Ye K, Chinnaiyan A, Halder G, Lai ZC, Guan KL Genes Dev. 2007 Nov 1. 21(21):2747-61. PubMed Journal

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Articles Citing pCMV-flag YAP2 5SA

Articles
LKB1 tumor suppressor regulates AMP kinase/mTOR-independent cell growth and proliferation via the phosphorylation of Yap. Nguyen HB, Babcock JT, Wells CD, Quilliam LA. Oncogene. 2013 Aug 29;32(35):4100-9. doi: 10.1038/onc.2012.431. Epub 2012 Oct 1. PubMed
Organ size control is dominant over Rb family inactivation to restrict proliferation in vivo. Ehmer U, Zmoos AF, Auerbach RK, Vaka D, Butte AJ, Kay MA, Sage J. Cell Rep. 2014 Jul 24;8(2):371-81. doi: 10.1016/j.celrep.2014.06.025. Epub 2014 Jul 10. PubMed
AMPK modulates Hippo pathway activity to regulate energy homeostasis. Wang W, Xiao ZD, Li X, Aziz KE, Gan B, Johnson RL, Chen J. Nat Cell Biol. 2015 Apr;17(4):490-9. doi: 10.1038/ncb3113. Epub 2015 Mar 9. PubMed
A feed-forward loop between lncARSR and YAP activity promotes expansion of renal tumour-initiating cells. Qu L, Wu Z, Li Y, Xu Z, Liu B, Liu F, Bao Y, Wu D, Liu J, Wang A, Chu X, Sun Y, Chen C, Zhang Z, Wang L. Nat Commun. 2016 Nov 25;7:12692. doi: 10.1038/ncomms12692. PubMed
Amotl1 mediates sequestration of the Hippo effector Yap1 downstream of Fat4 to restrict heart growth. Ragni CV, Diguet N, Le Garrec JF, Novotova M, Resende TP, Pop S, Charon N, Guillemot L, Kitasato L, Badouel C, Dufour A, Olivo-Marin JC, Trouve A, McNeill H, Meilhac SM. Nat Commun. 2017 Feb 27;8:14582. doi: 10.1038/ncomms14582. PubMed
Regulation of localization and function of the transcriptional co-activator YAP by angiomotin. Moleirinho S, Hoxha S, Mandati V, Curtale G, Troutman S, Ehmer U, Kissil JL. Elife. 2017 May 3;6. pii: e23966. doi: 10.7554/eLife.23966. PubMed
Dystrophin-glycoprotein complex sequesters Yap to inhibit cardiomyocyte proliferation. Morikawa Y, Heallen T, Leach J, Xiao Y, Martin JF. Nature. 2017 Jul 13;547(7662):227-231. doi: 10.1038/nature22979. Epub 2017 Jun 5. PubMed
YAP/TAZ and Hedgehog Coordinate Growth and Patterning in Gastrointestinal Mesenchyme. Cotton JL, Li Q, Ma L, Park JS, Wang J, Ou J, Zhu LJ, Ip YT, Johnson RL, Mao J. Dev Cell. 2017 Oct 9;43(1):35-47.e4. doi: 10.1016/j.devcel.2017.08.019. Epub 2017 Sep 21. PubMed
beta1 integrin-dependent Rac/group I PAK signaling mediates YAP activation of Yes-associated protein 1 (YAP1) via NF2/merlin. Sabra H, Brunner M, Mandati V, Wehrle-Haller B, Lallemand D, Ribba AS, Chevalier G, Guardiola P, Block MR, Bouvard D. J Biol Chem. 2017 Nov 24;292(47):19179-19197. doi: 10.1074/jbc.M117.808063. Epub 2017 Sep 29. PubMed
Hyaluronic acid enhances cell migration and invasion via the YAP1/TAZ-RHAMM axis in malignant pleural mesothelioma. Shigeeda W, Shibazaki M, Yasuhira S, Masuda T, Tanita T, Kaneko Y, Sato T, Sekido Y, Maesawa C. Oncotarget. 2017 Sep 8;8(55):93729-93740. doi: 10.18632/oncotarget.20750. eCollection 2017 Nov 7. PubMed
Enhanced YAP expression leads to EGFR TKI resistance in lung adenocarcinomas. Lee TF, Tseng YC, Nguyen PA, Li YC, Ho CC, Wu CW. Sci Rep. 2018 Jan 10;8(1):271. doi: 10.1038/s41598-017-18527-z. PubMed
KIBRA (WWC1) Is a Metastasis Suppressor Gene Affected by Chromosome 5q Loss in Triple-Negative Breast Cancer. Knight JF, Sung VYC, Kuzmin E, Couzens AL, de Verteuil DA, Ratcliffe CDH, Coelho PP, Johnson RM, Samavarchi-Tehrani P, Gruosso T, Smith HW, Lee W, Saleh SM, Zuo D, Zhao H, Guiot MC, Davis RR, Gregg JP, Moraes C, Gingras AC, Park M. Cell Rep. 2018 Mar 20;22(12):3191-3205. doi: 10.1016/j.celrep.2018.02.095. PubMed
Dishevelled has a YAP nuclear export function in a tumor suppressor context-dependent manner. Lee Y, Kim NH, Cho ES, Yang JH, Cha YH, Kang HE, Yun JS, Cho SB, Lee SH, Paclikova P, Radaszkiewicz TW, Bryja V, Kang CG, Yuk YS, Cha SY, Kim SY, Kim HS, Yook JI. Nat Commun. 2018 Jun 12;9(1):2301. doi: 10.1038/s41467-018-04757-w. PubMed
Contact inhibition controls cell survival and proliferation via YAP/TAZ-autophagy axis. Pavel M, Renna M, Park SJ, Menzies FM, Ricketts T, Fullgrabe J, Ashkenazi A, Frake RA, Lombarte AC, Bento CF, Franze K, Rubinsztein DC. Nat Commun. 2018 Jul 27;9(1):2961. doi: 10.1038/s41467-018-05388-x. PubMed
Loss of VGLL4 suppresses tumor PD-L1 expression and immune evasion. Wu A, Wu Q, Deng Y, Liu Y, Lu J, Liu L, Li X, Liao C, Zhao B, Song H. EMBO J. 2019 Jan 3;38(1). pii: embj.201899506. doi: 10.15252/embj.201899506. Epub 2018 Nov 5. PubMed
Caveolin-1 Modulates Mechanotransduction Responses to Substrate Stiffness through Actin-Dependent Control of YAP. Moreno-Vicente R, Pavon DM, Martin-Padura I, Catala-Montoro M, Diez-Sanchez A, Quilez-Alvarez A, Lopez JA, Sanchez-Alvarez M, Vazquez J, Strippoli R, Del Pozo MA. Cell Rep. 2018 Nov 6;25(6):1622-1635.e6. doi: 10.1016/j.celrep.2018.10.024. PubMed
Enigma proteins regulate YAP mechanotransduction. Elbediwy A, Vanyai H, Diaz-de-la-Loza MD, Frith D, Snijders AP, Thompson BJ. J Cell Sci. 2018 Nov 22;131(22). pii: jcs.221788. doi: 10.1242/jcs.221788. PubMed
The Hippo Pathway Prevents YAP/TAZ-Driven Hypertranscription and Controls Neural Progenitor Number. Lavado A, Park JY, Pare J, Finkelstein D, Pan H, Xu B, Fan Y, Kumar RP, Neale G, Kwak YD, McKinnon PJ, Johnson RL, Cao X. Dev Cell. 2018 Dec 3;47(5):576-591.e8. doi: 10.1016/j.devcel.2018.09.021. Epub 2018 Oct 25. PubMed
Luciferase Reporter Assays to Determine YAP/TAZ Activity in Mammalian Cells. Dupont S. Methods Mol Biol. 2019;1893:121-135. doi: 10.1007/978-1-4939-8910-2_11. PubMed
The antipsychotic chlorpromazine suppresses YAP signaling, stemness properties, and drug resistance in breast cancer cells. Yang CE, Lee WY, Cheng HW, Chung CH, Mi FL, Lin CW. Chem Biol Interact. 2019 Apr 1;302:28-35. doi: 10.1016/j.cbi.2019.01.033. Epub 2019 Jan 28. PubMed
YAP Partially Reprograms Chromatin Accessibility to Directly Induce Adult Cardiogenesis In Vivo. Monroe TO, Hill MC, Morikawa Y, Leach JP, Heallen T, Cao S, Krijger PHL, de Laat W, Wehrens XHT, Rodney GG, Martin JF. Dev Cell. 2019 Mar 25;48(6):765-779.e7. doi: 10.1016/j.devcel.2019.01.017. Epub 2019 Feb 14. PubMed
Yap/Taz regulate alveolar regeneration and resolution of lung inflammation. LaCanna R, Liccardo D, Zhang P, Tragesser L, Wang Y, Cao T, Chapman HA, Morrisey EE, Shen H, Koch WJ, Kosmider B, Wolfson MR, Tian Y. J Clin Invest. 2019 Apr 15;130:2107-2122. doi: 10.1172/JCI125014. eCollection 2019 Apr 15. PubMed
Linking YAP to Muller Glia Quiescence Exit in the Degenerative Retina. Hamon A, Garcia-Garcia D, Ail D, Bitard J, Chesneau A, Dalkara D, Locker M, Roger JE, Perron M. Cell Rep. 2019 May 7;27(6):1712-1725.e6. doi: 10.1016/j.celrep.2019.04.045. PubMed
Metastatic Colorectal Cancer Rewrites Metabolic Program Through a Glut3-YAP-dependent Signaling Circuit. Kuo CC, Ling HH, Chiang MC, Chung CH, Lee WY, Chu CY, Wu YC, Chen CH, Lai YW, Tsai IL, Cheng CH, Lin CW. Theranostics. 2019 Apr 13;9(9):2526-2540. doi: 10.7150/thno.32915. eCollection 2019. PubMed
Helicobacter pylori-induced YAP1 nuclear translocation promotes gastric carcinogenesis by enhancing IL-1beta expression. Wu Y, Shen L, Liang X, Li S, Ma L, Zheng L, Li T, Yu H, Chan H, Chen C, Yu J, Jia J. Cancer Med. 2019 Jul;8(8):3965-3980. doi: 10.1002/cam4.2318. Epub 2019 May 30. PubMed
The Myb-MuvB Complex Is Required for YAP-Dependent Transcription of Mitotic Genes. Pattschull G, Walz S, Grundl M, Schwab M, Ruhl E, Baluapuri A, Cindric-Vranesic A, Kneitz S, Wolf E, Ade CP, Rosenwald A, von Eyss B, Gaubatz S. Cell Rep. 2019 Jun 18;27(12):3533-3546.e7. doi: 10.1016/j.celrep.2019.05.071. PubMed
Src-mediated crosstalk between FXR and YAP protects against renal fibrosis. Kim DH, Choi HI, Park JS, Kim CS, Bae EH, Ma SK, Kim SW. FASEB J. 2019 Oct;33(10):11109-11122. doi: 10.1096/fj.201900325R. Epub 2019 Jul 12. PubMed
PR55alpha regulatory subunit of PP2A inhibits the MOB1/LATS cascade and activates YAP in pancreatic cancer cells. Hein AL, Brandquist ND, Ouellette CY, Seshacharyulu P, Enke CA, Ouellette MM, Batra SK, Yan Y. Oncogenesis. 2019 Oct 28;8(11):63. doi: 10.1038/s41389-019-0172-9. PubMed
Maintenance of Primary Hepatocyte Functions In Vitro by Inhibiting Mechanical Tension-Induced YAP Activation. Sun P, Zhang G, Su X, Jin C, Yu B, Yu X, Lv Z, Ma H, Zhang M, Wei W, Li W. Cell Rep. 2019 Dec 3;29(10):3212-3222.e4. doi: 10.1016/j.celrep.2019.10.128. PubMed
YAP-Mediated Recruitment of YY1 and EZH2 Represses Transcription of Key Cell-Cycle Regulators. Hoxha S, Shepard A, Troutman S, Diao H, Doherty JR, Janiszewska M, Witwicki RM, Pipkin ME, Ja WW, Kareta MS, Kissil JL. Cancer Res. 2020 Jun 15;80(12):2512-2522. doi: 10.1158/0008-5472.CAN-19-2415. Epub 2020 May 14. PubMed
Pivotal role of the transcriptional co-activator YAP in trophoblast stemness of the developing human placenta. Meinhardt G, Haider S, Kunihs V, Saleh L, Pollheimer J, Fiala C, Hetey S, Feher Z, Szilagyi A, Than NG, Knofler M. Proc Natl Acad Sci U S A. 2020 Jun 16;117(24):13562-13570. doi: 10.1073/pnas.2002630117. Epub 2020 Jun 1. PubMed
Angiocrine Sphingosine-1-Phosphate Activation of S1PR2-YAP Signaling Axis in Alveolar Type II Cells Is Essential for Lung Repair. Chen Q, Rehman J, Chan M, Fu P, Dudek SM, Natarajan V, Malik AB, Liu Y. Cell Rep. 2020 Jun 30;31(13):107828. doi: 10.1016/j.celrep.2020.107828. PubMed
Proline-rich tyrosine kinase 2 mediates transforming growth factor-beta-induced hepatic stellate cell activation and liver fibrosis. Kim J, Kang W, Kang SH, Park SH, Kim JY, Yang S, Ha SY, Paik YH. Sci Rep. 2020 Dec 3;10(1):21018. doi: 10.1038/s41598-020-78056-0. PubMed
Upregulation of CD109 Promotes the Epithelial-to-Mesenchymal Transition and Stemness Properties of Lung Adenocarcinomas via Activation of the Hippo-YAP Signaling. Lee KY, Kuo TC, Chou CM, Hsu WJ, Lee WC, Dai JZ, Wu SM, Lin CW. Cells. 2020 Dec 25;10(1). pii: cells10010028. doi: 10.3390/cells10010028. PubMed
A comprehensive enhancer screen identifies TRAM2 as a key and novel mediator of YAP oncogenesis. Li L, Ugalde AP, Scheele CLGJ, Dieter SM, Nagel R, Ma J, Pataskar A, Korkmaz G, Elkon R, Chien MP, You L, Su PR, Bleijerveld OB, Altelaar M, Momchev L, Manber Z, Han R, van Breugel PC, Lopes R, Ten Dijke P, van Rheenen J, Agami R. Genome Biol. 2021 Jan 29;22(1):54. doi: 10.1186/s13059-021-02272-8. PubMed
The Hippo Pathway Effector YAP Promotes Ferroptosis via the E3 Ligase SKP2. Yang WH, Lin CC, Wu J, Chao PY, Chen K, Chen PH, Chi JT. Mol Cancer Res. 2021 Jun;19(6):1005-1014. doi: 10.1158/1541-7786.MCR-20-0534. Epub 2021 Mar 11. PubMed
Transcriptional regulation of miR-30a by YAP impacts PTPN13 and KLF9 levels and Schwann cell proliferation. Shepard A, Hoxha S, Troutman S, Harbaugh D, Kareta MS, Kissil JL. J Biol Chem. 2021 Aug;297(2):100962. doi: 10.1016/j.jbc.2021.100962. Epub 2021 Jul 12. PubMed
Hippo signaling effectors YAP and TAZ induce Epstein-Barr Virus (EBV) lytic reactivation through TEADs in epithelial cells. Van Sciver N, Ohashi M, Pauly NP, Bristol JA, Nelson SE, Johannsen EC, Kenney SC. PLoS Pathog. 2021 Aug 2;17(8):e1009783. doi: 10.1371/journal.ppat.1009783. eCollection 2021 Aug. PubMed
Human Erbb2-induced Erk activity robustly stimulates cycling and functional remodeling of rat and human cardiomyocytes. Strash N, DeLuca S, Janer Carattini GL, Heo SC, Gorsuch R, Bursac N. Elife. 2021 Oct 19;10. pii: 65512. doi: 10.7554/eLife.65512. PubMed
YAP/TAZ drives cell proliferation and tumour growth via a polyamine-eIF5A hypusination-LSD1 axis. Li H, Wu BK, Kanchwala M, Cai J, Wang L, Xing C, Zheng Y, Pan D. Nat Cell Biol. 2022 Mar;24(3):373-383. doi: 10.1038/s41556-022-00848-5. Epub 2022 Feb 17. PubMed
Mechanical control of nuclear import by Importin-7 is regulated by its dominant cargo YAP. Garcia-Garcia M, Sanchez-Perales S, Jarabo P, Calvo E, Huyton T, Fu L, Ng SC, Sotodosos-Alonso L, Vazquez J, Casas-Tinto S, Gorlich D, Echarri A, Del Pozo MA. Nat Commun. 2022 Mar 4;13(1):1174. doi: 10.1038/s41467-022-28693-y. PubMed
Weight-bearing activity impairs nuclear membrane and genome integrity via YAP activation in plantar melanoma. Seo J, Kim H, Min KI, Kim C, Kwon Y, Zheng Z, Kim Y, Park HS, Ju YS, Roh MR, Chung KY, Kim J. Nat Commun. 2022 Apr 25;13(1):2214. doi: 10.1038/s41467-022-29925-x. PubMed
Yap controls notochord formation and neural tube patterning by integrating mechanotransduction with FoxA2 and Shh expression. Cheng C, Cong Q, Liu Y, Hu Y, Liang G, Dioneda KMM, Yang Y. Sci Adv. 2023 Jun 16;9(24):eadf6927. doi: 10.1126/sciadv.adf6927. Epub 2023 Jun 14. PubMed
Mitoguardin 1 and 2 promote granulosa cell proliferation by activating AKT and regulating the Hippo-YAP1 signaling pathway. Yan MQ, Zhu BH, Liu XH, Yang YM, Duan XY, Wang Y, Sun H, Feng M, Li T, Liu XM. Cell Death Dis. 2023 Nov 27;14(11):779. doi: 10.1038/s41419-023-06312-y. PubMed

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