pBS U3-hTR-500 Citations (6)
Originally described in: Distinct biogenesis pathways for human telomerase RNA and H/ACA small nucleolar RNAs.Fu D, Collins K Mol Cell. 2003 May . 11(5):1361-72. PubMed Journal
Articles Citing pBS U3-hTR-500
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| A novel autosomal recessive TERT T1129P mutation in a dyskeratosis congenita family leads to cellular senescence and loss of CD34+ hematopoietic stem cells not reversible by mTOR-inhibition. Stockklausner C, Raffel S, Klermund J, Bandapalli OR, Beier F, Brummendorf TH, Burger F, Sauer SW, Hoffmann GF, Lorenz H, Tagliaferri L, Nowak D, Hofmann WK, Buergermeister R, Kerber C, Rausch T, Korbel JO, Luke B, Trumpp A, Kulozik AE. Aging (Albany NY). 2015 Nov;7(11):911-27. PubMed |
| SMUG1 Promotes Telomere Maintenance through Telomerase RNA Processing. Kroustallaki P, Lirussi L, Carracedo S, You P, Esbensen QY, Gotz A, Jobert L, Alsoe L, Saetrom P, Gagos S, Nilsen H. Cell Rep. 2019 Aug 13;28(7):1690-1702.e10. doi: 10.1016/j.celrep.2019.07.040. PubMed |
| Thymidine nucleotide metabolism controls human telomere length. Mannherz W, Agarwal S. Nat Genet. 2023 Apr;55(4):568-580. doi: 10.1038/s41588-023-01339-5. Epub 2023 Mar 23. PubMed |
TCAB1 prevents nucleolar accumulation of the telomerase RNA to facilitate telomerase assembly.
Klump BM, Perez GI, Patrick EM, Adams-Boone K, Cohen SB, Han L, Yu K, Schmidt JC.
Cell Rep. 2023 Jun 1;42(6):112577. doi: 10.1016/j.celrep.2023.112577.
PubMed
Associated Plasmids |
| Chemotherapeutic 6-thio-2'-deoxyguanosine selectively targets and inhibits telomerase by inducing a non-productive telomere-bound telomerase complex. Sanford SL, Badstubner M, Gerber M, Mannherz W, Lampl N, Dannenberg R, Hinchie A, Schaich MA, Myong S, Hedglin M, Agarwal S, Alder JK, Stone MD, Opresko PL. bioRxiv [Preprint]. 2025 Feb 19:2025.02.05.636339. doi: 10.1101/2025.02.05.636339. PubMed |
| Metabolic constraint of human telomere length by nucleotide salvage efficiency. Mannherz W, Crompton A, Lampl N, Agarwal S. Nat Commun. 2025 Mar 27;16(1):3000. doi: 10.1038/s41467-025-58221-7. PubMed |
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