Flag Leucyl tRNA synthetase pRK5 Citations (2)

Originally described in: A Tumor suppressor complex with GAP activity for the Rag GTPases that signal amino acid sufficiency to mTORC1.
Bar-Peled L, Chantranupong L, Cherniack AD, Chen WW, Ottina KA, Grabiner BC, Spear ED, Carter SL, Meyerson M, Sabatini DM Science. 2013 May 31;340(6136):1100-6. doi: 10.1126/science.1232044. PubMed Journal

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Articles Citing Flag Leucyl tRNA synthetase pRK5

Articles
Transposon mutagenesis reveals fludarabine-resistance mechanisms in chronic lymphocytic leukemia. Pandzic T, Larsson J, He L, Kundu S, Ban K, Akhtar-Ali M, Hellstrom AR, Schuh A, Clifford R, Blakemore SJ, Strefford JC, Bauman TS, Lopez-Guillermo A, Campo E, Ljungstrom V, Mansouri L, Rosenquist R, Sjoblom T, Hellstrom M. Clin Cancer Res. 2016 Mar 8. pii: clincanres.2903.2015. PubMed
The amino acid metabolite homocysteine activates mTORC1 to inhibit autophagy and form abnormal proteins in human neurons and mice. Khayati K, Antikainen H, Bonder EM, Weber GF, Kruger WD, Jakubowski H, Dobrowolski R. FASEB J. 2017 Feb;31(2):598-609. doi: 10.1096/fj.201600915R. Epub 2016 Oct 25. PubMed

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