eGFP Depdc5 pLJM1 Citations (3)

Originally described in: A Tumor suppressor complex with GAP activity for the Rag GTPases that signal amino acid sufficiency to mTORC1.
Bar-Peled L, Chantranupong L, Cherniack AD, Chen WW, Ottina KA, Grabiner BC, Spear ED, Carter SL, Meyerson M, Sabatini DM Science. 2013 May 31;340(6136):1100-6. doi: 10.1126/science.1232044. PubMed Journal

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Articles Citing eGFP Depdc5 pLJM1

Articles
DEPDC5 deficiency contributes to resistance to leucine starvation via p62 accumulation in hepatocellular carcinoma. Mizuno Y, Shimada S, Akiyama Y, Watanabe S, Aida T, Ogawa K, Ono H, Mitsunori Y, Ban D, Kudo A, Arii S, Yamaoka S, Tanabe M, Tanaka S. Sci Rep. 2018 Jan 8;8(1):106. doi: 10.1038/s41598-017-18323-9. PubMed
Src regulates amino acid-mediated mTORC1 activation by disrupting GATOR1-Rag GTPase interaction. Pal R, Palmieri M, Chaudhury A, Klisch TJ, di Ronza A, Neilson JR, Rodney GG, Sardiello M. Nat Commun. 2018 Oct 19;9(1):4351. doi: 10.1038/s41467-018-06844-4. PubMed
Graded activation of the CLEAR network through mTORC1 suppression on cargo-harboring lysosomes. Hsieh CW, Chen GC, Yang WY. Cell Rep. 2026 Apr 9;45(4):117228. doi: 10.1016/j.celrep.2026.117228. PubMed

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