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pAC94-pmax-dCas9VP160-2A-puro Citations (7)

Plasmid Article: Multiplexed activation of endogenous genes by CRISPR-on, an RNA-guided transcriptional activator system.
Cheng AW, Wang H, Yang H, Shi L, Katz Y, Theunissen TW, Rangarajan S, Shivalila CS, Dadon DB, Jaenisch R Cell Res. 2013 Aug 27. doi: 10.1038/cr.2013.122.
PubMed Journal

Articles Citing pAC94-pmax-dCas9VP160-2A-puro

CRISPR-on system for the activation of the endogenous human INS gene. Gimenez CA, Ielpi M, Mutto A, Grosembacher L, Argibay P, Pereyra-Bonnet F. Gene Ther. 2016 Jun;23(6):543-7. doi: 10.1038/gt.2016.28. Epub 2016 Apr 4. PubMed
Psip1/p52 regulates posterior Hoxa genes through activation of lncRNA Hottip. Pradeepa MM, McKenna F, Taylor GC, Bengani H, Grimes GR, Wood AJ, Bhatia S, Bickmore WA. PLoS Genet. 2017 Apr 6;13(4):e1006677. doi: 10.1371/journal.pgen.1006677. eCollection 2017 Apr. PubMed
Agonist-induced dimer dissociation as a macromolecular step in G protein-coupled receptor signaling. Petersen J, Wright SC, Rodriguez D, Matricon P, Lahav N, Vromen A, Friedler A, Stromqvist J, Wennmalm S, Carlsson J, Schulte G. Nat Commun. 2017 Aug 9;8(1):226. doi: 10.1038/s41467-017-00253-9. PubMed
dCas9-Based Scn1a Gene Activation Restores Inhibitory Interneuron Excitability and Attenuates Seizures in Dravet Syndrome Mice. Colasante G, Lignani G, Brusco S, Di Berardino C, Carpenter J, Giannelli S, Valassina N, Bido S, Ricci R, Castoldi V, Marenna S, Church T, Massimino L, Morabito G, Benfenati F, Schorge S, Leocani L, Kullmann DM, Broccoli V. Mol Ther. 2020 Jan 8;28(1):235-253. doi: 10.1016/j.ymthe.2019.08.018. Epub 2019 Sep 3. PubMed
HOTTIP lncRNA Promotes Hematopoietic Stem Cell Self-Renewal Leading to AML-like Disease in Mice. Luo H, Zhu G, Xu J, Lai Q, Yan B, Guo Y, Fung TK, Zeisig BB, Cui Y, Zha J, Cogle C, Wang F, Xu B, Yang FC, Li W, So CWE, Qiu Y, Xu M, Huang S. Cancer Cell. 2019 Dec 9;36(6):645-659.e8. doi: 10.1016/j.ccell.2019.10.011. Epub 2019 Nov 27. PubMed
The MITF-SOX10 regulated long non-coding RNA DIRC3 is a melanoma tumour suppressor. Coe EA, Tan JY, Shapiro M, Louphrasitthiphol P, Bassett AR, Marques AC, Goding CR, Vance KW. PLoS Genet. 2019 Dec 27;15(12):e1008501. doi: 10.1371/journal.pgen.1008501. eCollection 2019 Dec. PubMed
In vivo CRISPRa decreases seizures and rescues cognitive deficits in a rodent model of epilepsy. Colasante G, Qiu Y, Massimino L, Di Berardino C, Cornford JH, Snowball A, Weston M, Jones SP, Giannelli S, Lieb A, Schorge S, Kullmann DM, Broccoli V, Lignani G. Brain. 2020 Mar 1;143(3):891-905. doi: 10.1093/brain/awaa045. PubMed

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