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pHRIG-AktDN Citations (6)

Originally described in: Akt isoforms differentially protect against stroke-induced neuronal injury by regulating mTOR activities.
Xie R, Cheng M, Li M, Xiong X, Daadi M, Sapolsky RM, Zhao H J Cereb Blood Flow Metab. 2013 Dec;33(12):1875-85. doi: 10.1038/jcbfm.2013.132. Epub 2013 Aug 14.
PubMed Journal

Articles Citing pHRIG-AktDN

MYC Drives Pten/Trp53-Deficient Proliferation and Metastasis due to IL6 Secretion and AKT Suppression via PHLPP2. Nowak DG, Cho H, Herzka T, Watrud K, DeMarco DV, Wang VM, Senturk S, Fellmann C, Ding D, Beinortas T, Kleinman D, Chen M, Sordella R, Wilkinson JE, Castillo-Martin M, Cordon-Cardo C, Robinson BD, Trotman LC. Cancer Discov. 2015 Jun;5(6):636-51. doi: 10.1158/2159-8290.CD-14-1113. Epub 2015 Mar 31. PubMed
Alpha-synuclein suppresses mitochondrial protease ClpP to trigger mitochondrial oxidative damage and neurotoxicity. Hu D, Sun X, Liao X, Zhang X, Zarabi S, Schimmer A, Hong Y, Ford C, Luo Y, Qi X. Acta Neuropathol. 2019 Jun;137(6):939-960. doi: 10.1007/s00401-019-01993-2. Epub 2019 Mar 15. PubMed
Cerebral organoid and mouse models reveal a RAB39b-PI3K-mTOR pathway-dependent dysregulation of cortical development leading to macrocephaly/autism phenotypes. Zhang W, Ma L, Yang M, Shao Q, Xu J, Lu Z, Zhao Z, Chen R, Chai Y, Chen JF. Genes Dev. 2020 Apr 1;34(7-8):580-597. doi: 10.1101/gad.332494.119. Epub 2020 Feb 27. PubMed
Presynaptic APP levels and synaptic homeostasis are regulated by Akt phosphorylation of huntingtin. Bruyere J, Abada YS, Vitet H, Fontaine G, Deloulme JC, Ces A, Denarier E, Pernet-Gallay K, Andrieux A, Humbert S, Potier MC, Delatour B, Saudou F. Elife. 2020 May 26;9:e56371. doi: 10.7554/eLife.56371. PubMed
c-Jun acts downstream of PI3K/AKT signaling to mediate the effect of leptin on methionine adenosyltransferase 2B in hepatic stellate cells in vitro and in vivo. Zhu X, Jia X, Cheng F, Tian H, Zhou Y. J Pathol. 2020 Dec;252(4):423-432. doi: 10.1002/path.5536. Epub 2020 Sep 26. PubMed
Oligodendroglial glycolytic stress triggers inflammasome activation and neuropathology in Alzheimer's disease. Zhang X, Wang R, Hu D, Sun X, Fujioka H, Lundberg K, Chan ER, Wang Q, Xu R, Flanagan ME, Pieper AA, Qi X. Sci Adv. 2020 Dec 4;6(49). pii: 6/49/eabb8680. doi: 10.1126/sciadv.abb8680. Print 2020 Dec. PubMed

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