Perturb-seq GBC library Citations (8)

Originally described in: A Multiplexed Single-Cell CRISPR Screening Platform Enables Systematic Dissection of the Unfolded Protein Response.
Adamson B, Norman TM, Jost M, Cho MY, Nunez JK, Chen Y, Villalta JE, Gilbert LA, Horlbeck MA, Hein MY, Pak RA, Gray AN, Gross CA, Dixit A, Parnas O, Regev A, Weissman JS Cell. 2016 Dec 15;167(7):1867-1882.e21. doi: 10.1016/j.cell.2016.11.048. PubMed Journal

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Articles Citing Perturb-seq GBC library

Articles
CHD7 and Runx1 interaction provides a braking mechanism for hematopoietic differentiation. Hsu J, Huang HT, Lee CT, Choudhuri A, Wilson NK, Abraham BJ, Moignard V, Kucinski I, Yu S, Hyde RK, Tober J, Cai X, Li Y, Guo Y, Yang S, Superdock M, Trompouki E, Calero-Nieto FJ, Ghamari A, Jiang J, Gao P, Gao L, Nguyen V, Robertson AL, Durand EM, Kathrein KL, Aifantis I, Gerber SA, Tong W, Tan K, Cantor AB, Zhou Y, Liu PP, Young RA, Gottgens B, Speck NA, Zon LI. Proc Natl Acad Sci U S A. 2020 Sep 22;117(38):23626-23635. doi: 10.1073/pnas.2003228117. Epub 2020 Sep 3. PubMed
Interactions between lineage-associated transcription factors govern haematopoietic progenitor states. Kucinski I, Wilson NK, Hannah R, Kinston SJ, Cauchy P, Lenaerts A, Grosschedl R, Gottgens B. EMBO J. 2020 Dec 15;39(24):e104983. doi: 10.15252/embj.2020104983. Epub 2020 Oct 26. PubMed
Modeling glioblastoma heterogeneity as a dynamic network of cell states. Larsson I, Dalmo E, Elgendy R, Niklasson M, Doroszko M, Segerman A, Jornsten R, Westermark B, Nelander S. Mol Syst Biol. 2021 Sep;17(9):e10105. doi: 10.15252/msb.202010105. PubMed
The myogenesis program drives clonal selection and drug resistance in rhabdomyosarcoma. Patel AG, Chen X, Huang X, Clay MR, Komorova N, Krasin MJ, Pappo A, Tillman H, Orr BA, McEvoy J, Gordon B, Blankenship K, Reilly C, Zhou X, Norrie JL, Karlstrom A, Yu J, Wodarz D, Stewart E, Dyer MA. Dev Cell. 2022 May 23;57(10):1226-1240.e8. doi: 10.1016/j.devcel.2022.04.003. Epub 2022 Apr 27. PubMed
Structural and functional properties of mSWI/SNF chromatin remodeling complexes revealed through single-cell perturbation screens. Otto JE, Ursu O, Wu AP, Winter EB, Cuoco MS, Ma S, Qian K, Michel BC, Buenrostro JD, Berger B, Regev A, Kadoch C. Mol Cell. 2023 Apr 20;83(8):1350-1367.e7. doi: 10.1016/j.molcel.2023.03.013. Epub 2023 Apr 6. PubMed
Focal adhesion kinase-YAP signaling axis drives drug-tolerant persister cells and residual disease in lung cancer. Haderk F, Chou YT, Cech L, Fernandez-Mendez C, Yu J, Olivas V, Meraz IM, Barbosa Rabago D, Kerr DL, Gomez C, Allegakoen DV, Guan J, Shah KN, Herrington KA, Gbenedio OM, Nanjo S, Majidi M, Tamaki W, Pourmoghadam YK, Rotow JK, McCoach CE, Riess JW, Gutkind JS, Tang TT, Post L, Huang B, Santisteban P, Goodarzi H, Bandyopadhyay S, Kuo CJ, Roose JP, Wu W, Blakely CM, Roth JA, Bivona TG. Nat Commun. 2024 May 3;15(1):3741. doi: 10.1038/s41467-024-47423-0. PubMed
Multi-omic lineage tracing predicts the transcriptional, epigenetic and genetic determinants of cancer evolution. Nadalin F, Marzi MJ, Pirra Piscazzi M, Fuentes-Bravo P, Procaccia S, Climent M, Bonetti P, Rubolino C, Giuliani B, Papatheodorou I, Marioni JC, Nicassio F. Nat Commun. 2024 Sep 1;15(1):7609. doi: 10.1038/s41467-024-51424-4. PubMed
Dissecting cellular ecosystem with single-cell CRISPR screens. Liu Z, Lan Z, Kang X, Yao Y, Rao S. Blood Sci. 2025 Dec 4;7(4):e00266. doi: 10.1097/BS9.0000000000000266. eCollection 2025 Dec. PubMed

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