Human Integrin beta 2 Citations (4)

Originally described in: Cloning of the beta subunit of the leukocyte adhesion proteins: homology to an extracellular matrix receptor defines a novel supergene family.
Kishimoto TK, O'Connor K, Lee A, Roberts TM, Springer TA Cell 1987 Feb 27;48(4):681-90. PubMed Journal

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Articles Citing Human Integrin beta 2

Articles
Cathepsin X cleavage of the beta2 integrin regulates talin-binding and LFA-1 affinity in T cells. Jevnikar Z, Obermajer N, Doljak B, Turk S, Gobec S, Svajger U, Hailfinger S, Thome M, Kos J. J Leukoc Biol. 2011 Jul;90(1):99-109. doi: 10.1189/jlb.1110622. Epub 2011 Mar 31. PubMed
Integrin CD11c/CD18 alpha-chain phosphorylation is functionally important. Uotila LM, Aatonen M, Gahmberg CG. J Biol Chem. 2013 Nov 15;288(46):33494-9. doi: 10.1074/jbc.C113.497446. Epub 2013 Oct 15. PubMed
Phosphorylation of the alpha-chain in the integrin LFA-1 enables beta2-chain phosphorylation and alpha-actinin binding required for cell adhesion. Jahan F, Madhavan S, Rolova T, Viazmina L, Gronholm M, Gahmberg CG. J Biol Chem. 2018 Aug 10;293(32):12318-12330. doi: 10.1074/jbc.RA118.004318. Epub 2018 Jun 14. PubMed
Human LFA-1 governs T cell immune surveillance of the skin. Yatim A, Youssefian L, Idani A, Mourelatos H, Alipour Olyaei N, Habibi L, Peel JN, Gaballa M, Kim C, Lee D, Le Floc'h C, Chan YH, Martin-Fernandez M, Pelletier L, Nakajima K, Fayand A, Momenilandi M, Seeleuthner Y, Chaldebas M, Saeidian AH, Mahmoudi H, Nikbakht N, Deswarte C, Kerrouche N, Sahel H, Parvaneh N, Tamizifar B, Sherkat R, Chanal J, Firooz A, Alizadeh Z, Lorenzo-Diaz L, Mariaggi AA, Ogishi M, Diep A, Hammadi B, Kerrouche N, Rinchai D, Sedighzadeh S, Mehrjooy S, Akrami SM, Lenormand C, Radosavljevic M, Rosain J, Zhang SY, Boisson B, Zhang P, Boisson-Dupuis S, Krueger JG, Pretet JL, Waterboer T, Pourpak Z, Fazlollahi MR, Abel L, Bogunovic D, Shahrooei M, Cobat A, Carapito R, Molitor A, Vahidnezhad H, Beziat V, Bahram S, Jouanguy E, Casanova JL. Sci Immunol. 2026 Feb 27;11(116):eadz8360. doi: 10.1126/sciimmunol.adz8360. Epub 2026 Feb 27. PubMed

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