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pRK7-HA-S6K1-WT Citations (22)

Plasmid Article: Identification of a conserved motif required for mTOR signaling.
Schalm SS, Blenis J Curr Biol. 2002 Apr 16. 12(8):632-9.
PubMed Journal

Articles Citing pRK7-HA-S6K1-WT

S6K directly phosphorylates IRS-1 on Ser-270 to promote insulin resistance in response to TNF-(alpha) signaling through IKK2. Zhang J, Gao Z, Yin J, Quon MJ, Ye J. J Biol Chem. 2008 Dec 19;283(51):35375-82. doi: 10.1074/jbc.M806480200. Epub 2008 Oct 24. PubMed
Inactivation of NF-kappaB p50 leads to insulin sensitization in liver through post-translational inhibition of p70S6K. Gao Z, Yin J, Zhang J, He Q, McGuinness OP, Ye J. J Biol Chem. 2009 Jul 3;284(27):18368-76. doi: 10.1074/jbc.M109.007260. Epub 2009 May 11. PubMed
Rictor is a novel target of p70 S6 kinase-1. Treins C, Warne PH, Magnuson MA, Pende M, Downward J. Oncogene. 2009 Nov 23. ():. PubMed
mTOR-mediated activation of p70 S6K induces differentiation of pluripotent human embryonic stem cells. Easley CA 4th, Ben-Yehudah A, Redinger CJ, Oliver SL, Varum ST, Eisinger VM, Carlisle DL, Donovan PJ, Schatten GP. Cell Reprogram. 2010 Jun;12(3):263-73. doi: 10.1089/cell.2010.0011. PubMed
The identification of raptor as a substrate for p44/42 MAPK. Langlais P, Yi Z, Mandarino LJ. Endocrinology. 2011 Apr;152(4):1264-73. doi: 10.1210/en.2010-1271. Epub 2011 Feb 15. PubMed
Phosphorylation of eukaryotic translation initiation factor 4B (EIF4B) by open reading frame 45/p90 ribosomal S6 kinase (ORF45/RSK) signaling axis facilitates protein translation during Kaposi sarcoma-associated herpesvirus (KSHV) lytic replication. Kuang E, Fu B, Liang Q, Myoung J, Zhu F. J Biol Chem. 2011 Dec 2;286(48):41171-82. doi: 10.1074/jbc.M111.280982. Epub 2011 Oct 12. PubMed
Large FK506-binding proteins shape the pharmacology of rapamycin. Marz AM, Fabian AK, Kozany C, Bracher A, Hausch F. Mol Cell Biol. 2013 Apr;33(7):1357-67. doi: 10.1128/MCB.00678-12. Epub 2013 Jan 28. PubMed
InterAKTions with FKBPs--mutational and pharmacological exploration. Fabian AK, Marz A, Neimanis S, Biondi RM, Kozany C, Hausch F. PLoS One. 2013;8(2):e57508. doi: 10.1371/journal.pone.0057508. Epub 2013 Feb 28. PubMed
Dissecting the functional interplay between the TOR pathway and the cilium in zebrafish. Yuan S, Zhao L, Sun Z. Methods Enzymol. 2013;525:159-89. doi: 10.1016/B978-0-12-397944-5.00009-2. PubMed
mTORC1 dependent regulation of REDD1 protein stability. Tan CY, Hagen T. PLoS One. 2013 May 22;8(5):e63970. doi: 10.1371/journal.pone.0063970. Print 2013. PubMed
Characteristics and requirements of basal autophagy in HEK 293 cells. Musiwaro P, Smith M, Manifava M, Walker SA, Ktistakis NT. Autophagy. 2013 Sep;9(9):1407-17. doi: 10.4161/auto.25455. Epub 2013 Jun 20. PubMed
Phosphorylation and degradation of S6K1 (p70S6K1) in response to persistent JNK1 Activation. Zhang J, Gao Z, Ye J. Biochim Biophys Acta. 2013 Dec;1832(12):1980-8. doi: 10.1016/j.bbadis.2013.06.013. Epub 2013 Jun 28. PubMed
Rapamycin and interleukin-1beta impair brain-derived neurotrophic factor-dependent neuron survival by modulating autophagy. Smith ED, Prieto GA, Tong L, Sears-Kraxberger I, Rice JD, Steward O, Cotman CW. J Biol Chem. 2014 Jul 25;289(30):20615-29. PubMed
S6K1 controls autophagosome maturation in autophagy induced by sulforaphane or serum deprivation. Hac A, Domachowska A, Narajczyk M, Cyske K, Pawlik A, Herman-Antosiewicz A. Eur J Cell Biol. 2015 Oct;94(10):470-81. doi: 10.1016/j.ejcb.2015.05.001. Epub 2015 May 29. PubMed
The CREB coactivator CRTC2 controls hepatic lipid metabolism by regulating SREBP1. Han J, Li E, Chen L, Zhang Y, Wei F, Liu J, Deng H, Wang Y. Nature. 2015 Aug 13;524(7564):243-6. doi: 10.1038/nature14557. Epub 2015 Jul 6. PubMed
The PtdIns3-phosphatase MTMR3 interacts with mTORC1 and suppresses its activity. Hao F, Itoh T, Morita E, Shirahama-Noda K, Yoshimori T, Noda T. FEBS Lett. 2016 Jan;590(1):161-73. doi: 10.1002/1873-3468.12048. Epub 2015 Dec 31. PubMed
Leucine induced dephosphorylation of Sestrin2 promotes mTORC1 activation. Kimball SR, Gordon BS, Moyer JE, Dennis MD, Jefferson LS. Cell Signal. 2016 Aug;28(8):896-906. doi: 10.1016/j.cellsig.2016.03.008. Epub 2016 Mar 21. PubMed
Growth of the mammalian Golgi during interphase. Sin AT, Harrison RE. Mol Cell Biol. 2016 Jun 20. pii: MCB.00046-16. PubMed
RACK1 is an Interaction Partner of ATG5 and a Novel Regulator of Autophagy. Erbil S, Oral O, Mitou G, Kig C, Durmaz-Timucin E, Guven-Maiorov E, Gulacti F, Gokce G, Dengjel J, Sezerman OU, Gozuacik D. J Biol Chem. 2016 Jun 20. pii: jbc.M115.708081. PubMed
G protein-dependent signaling triggers a beta-arrestin-scaffolded p70S6K/ rpS6 module that controls 5'TOP mRNA translation. Trefier A, Musnier A, Landomiel F, Bourquard T, Boulo T, Ayoub MA, Leon K, Bruneau G, Chevalier M, Durand G, Blache MC, Inoue A, Fontaine J, Gauthier C, Tesseraud S, Reiter E, Poupon A, Crepieux P. FASEB J. 2018 Mar;32(3):1154-1169. doi: 10.1096/fj.201700763R. Epub 2018 Jan 3. PubMed
The mTOR-S6 kinase pathway promotes stress granule assembly. Sfakianos AP, Mellor LE, Pang YF, Kritsiligkou P, Needs H, Abou-Hamdan H, Desaubry L, Poulin GB, Ashe MP, Whitmarsh AJ. Cell Death Differ. 2018 Nov;25(10):1766-1780. doi: 10.1038/s41418-018-0076-9. Epub 2018 Mar 9. PubMed
Mammalian EAK-7 activates alternative mTOR signaling to regulate cell proliferation and migration. Nguyen JT, Ray C, Fox AL, Mendonca DB, Kim JK, Krebsbach PH. Sci Adv. 2018 May 9;4(5):eaao5838. doi: 10.1126/sciadv.aao5838. eCollection 2018 May. PubMed

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