pcDNA5-Flag-BRD4-WT Citations (9)
Originally described in: Response and resistance to BET bromodomain inhibitors in triple-negative breast cancer.Shu S, Lin CY, He HH, Witwicki RM, Tabassum DP, Roberts JM, Janiszewska M, Huh SJ, Liang Y, Ryan J, Doherty E, Mohammed H, Guo H, Stover DG, Ekram MB, Peluffo G, Brown J, D'Santos C, Krop IE, Dillon D, McKeown M, Ott C, Qi J, Ni M, Rao PK, Duarte M, Wu SY, Chiang CM, Anders L, Young RA, Winer EP, Letai A, Barry WT, Carroll JS, Long HW, Brown M, Liu XS, Meyer CA, Bradner JE, Polyak K Nature. 2016 Jan 21;529(7586):413-7. doi: 10.1038/nature16508. Epub 2016 Jan 6. PubMed Journal
Articles Citing pcDNA5-Flag-BRD4-WT
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| Transcriptional addiction in cancer cells is mediated by YAP/TAZ through BRD4. Zanconato F, Battilana G, Forcato M, Filippi L, Azzolin L, Manfrin A, Quaranta E, Di Biagio D, Sigismondo G, Guzzardo V, Lejeune P, Haendler B, Krijgsveld J, Fassan M, Bicciato S, Cordenonsi M, Piccolo S. Nat Med. 2018 Oct;24(10):1599-1610. doi: 10.1038/s41591-018-0158-8. Epub 2018 Sep 17. PubMed |
| Bromodomain-Containing Protein 4 (BRD4) Inhibition Sensitizes Palomid 529-Induced Anti-Renal Cell Carcinoma Cell Activity in Vitro and in Vivo. Xing ZY, Wang Y, Cheng L, Chen J, He XZ, Xing W. Cell Physiol Biochem. 2018;50(2):640-653. doi: 10.1159/000494185. Epub 2018 Oct 11. PubMed |
| Structure-guided drug design identifies a BRD4-selective small molecule that suppresses HIV. Niu Q, Liu Z, Alamer E, Fan X, Chen H, Endsley J, Gelman BB, Tian B, Kim JH, Michael NL, Robb ML, Ananworanich J, Zhou J, Hu H. J Clin Invest. 2019 Jul 22;129(8):3361-3373. doi: 10.1172/JCI120633. eCollection 2019 Jul 22. PubMed |
| VDAC1 is regulated by BRD4 and contributes to JQ1 resistance in breast cancer. Yang G, Zhou D, Li J, Wang W, Zhong W, Fan W, Yu M, Cheng H. Oncol Lett. 2019 Sep;18(3):2340-2347. doi: 10.3892/ol.2019.10534. Epub 2019 Jun 27. PubMed |
| Cis-acting lnc-eRNA SEELA directly binds histone H4 to promote histone recognition and leukemia progression. Fang K, Huang W, Sun YM, Chen TQ, Zeng ZC, Yang QQ, Pan Q, Han C, Sun LY, Luo XQ, Wang WT, Chen YQ. Genome Biol. 2020 Nov 3;21(1):269. doi: 10.1186/s13059-020-02186-x. PubMed |
| Stromal induction of BRD4 phosphorylation Results in Chromatin Remodeling and BET inhibitor Resistance in Colorectal Cancer. Wang W, Tang YA, Xiao Q, Lee WC, Cheng B, Niu Z, Oguz G, Feng M, Lee PL, Li B, Yang ZH, Chen YF, Lan P, Wu XJ, Yu Q. Nat Commun. 2021 Jul 21;12(1):4441. doi: 10.1038/s41467-021-24687-4. PubMed |
| A light-switching pyrene probe to detect phase-separated biomolecules. Hazawa M, Amemori S, Nishiyama Y, Iga Y, Iwashima Y, Kobayashi A, Nagatani H, Mizuno M, Takahashi K, Wong RW. iScience. 2021 Jul 15;24(8):102865. doi: 10.1016/j.isci.2021.102865. eCollection 2021 Aug 20. PubMed |
| Cloning BRD4 long isoform into overexpression vectors for stable overexpression of BRD4-L in mammalian cells. Drumond-Bock AL, Cybula M, Wang L, Wang L, Bieniasz M. STAR Protoc. 2022 Oct 26;3(4):101785. doi: 10.1016/j.xpro.2022.101785. eCollection 2022 Dec 16. PubMed |
| BRD4 binds to active cranial neural crest enhancers to regulate RUNX2 activity during osteoblast differentiation. Musa RE, Lester KL, Quickstad G, Vardabasso S, Shumate TV, Salcido RT, Ge K, Shpargel KB. Development. 2024 Jan 15;151(2):dev202110. doi: 10.1242/dev.202110. Epub 2024 Jan 24. PubMed |
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