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Institute for Protein Innovation Antibody Collection

Welcome to the Institute for Protein Innovation (IPI) Collection!

Here, you’ll find unique recombinant antibodies targeting families of cell surface and secreted proteins.

The majority of antibodies in the collection have been developed using a platform (Link opens in a new window) based on yeast display technology (Link opens in a new window) and an optimized sorting process. This combination allows IPI to generate antibodies to highly conserved proteins and other difficult-to-target antigens that are intractable via animal immunization.

IPI is a nonprofit research organization with a mission to advance protein science to accelerate research and improve human health. As part of that mission, IPI is providing access to high-quality, well-characterized antibodies in an open science model.

Integrin Antibodies

Integrins are a family of mechanotransduction receptors, comprised of alpha-beta subunit heterodimers. The IPI collection contains antibodies that uniquely:

  1. Bind to the alpha subunit, outside the ligand-binding pocket
  2. Bind to the beta subunit, outside the ligand-binding pocket
  3. Bind specific subunit pairs, outside the ligand-binding pocket
  4. Bind specific subunit pairs, blocking ligand binding and receptor function
Integrin antibody can be one of fours types, as described in text.
Figure courtesy of IPI

Available Antibodies

ID Recombinant Antibody Description Isotype Recommended Applications