The activity of a human endoplasmic reticulum-associated degradation E3, gp78, requires its Cue domain, RING finger, and an E2-binding site.
Chen B, Mariano J, Tsai YC, Chan AH, Cohen M, Weissman AM
Proc Natl Acad Sci U S A. 2006 Jan 10. 103(2):341-6. PubMed Article
Chen B, Mariano J, Tsai YC, Chan AH, Cohen M, Weissman AM
Proc Natl Acad Sci U S A. 2006 Jan 10. 103(2):341-6. PubMed Article
Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 13305 | pCI-Neo-gp78 Cue-m1,2 / JM22 | |
| 13306 | pCI-Neo-gp78 G2BR mt / JM23 | |
| 13307 | pGEX4T2 gp78 CD-m1,2 / JM25 | |
| 13308 | pGEX4T2 gp78 G2BR mt / JM26 | |
| 201813 | UBE2G2 shRNA | siRNA |