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The KLHL12-Cullin-3 ubiquitin ligase negatively regulates the Wnt-beta-catenin pathway by targeting Dishevelled for degradation.
Angers S, Thorpe CJ, Biechele TL, Goldenberg SJ, Zheng N, MacCoss MJ, Moon RT
Nat Cell Biol. 2006 Apr . 8(4):348-57.
PubMed Article

Plasmids from Article

ID Plasmid Purpose  
15100V51 pIRESpuro-GLUE (pGLUE) tandem-affinity purification plasmid; streptavidin-(streptag) and calmodulin-(CBP) binding affinity tags
15101M76 pIRESpuro-GLUE-hDsh2
15102M77 pIRESpuro-GLUE-hDsh3

Recombinant Antibodies from Article