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STAT3-driven transcription depends upon the dimethylation of K49 by EZH2.
Dasgupta M, Dermawan JK, Willard B, Stark GR
Proc Natl Acad Sci U S A. 2015 Mar 31;112(13):3985-90. doi: 10.1073/pnas.1503152112. Epub 2015 Mar 12.
PubMed Article

Plasmids from Article

ID Plasmid Purpose  
71446pLEGFP-S727A-STAT3Retroviral expression of S727A-STAT3. Please note that this plasmid contains S727A-STAT3 tagged with FLAG, not GFP.
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71447pLEGFP-K49R-STAT3Retroviral expression of K49R-STAT3. Please note that this plasmid contains K49R-STAT3 tagged with FLAG, not GFP.
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71448pLEGFP-K140R-STAT3Retroviral expression of K140R-STAT3. Please note that this plasmid contains K140R-STAT3 tagged with FLAG, not GFP.
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71449pLEGFP-K685R-STAT3Retroviral expression of K685R-STAT3. Please note that this plasmid contains K685R-STAT3 tagged with FLAG, not GFP.
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