Ras-GTP dimers activate the Mitogen-Activated Protein Kinase (MAPK) pathway.
Nan X, Tamguney TM, Collisson EA, Lin LJ, Pitt C, Galeas J, Lewis S, Gray JW, McCormick F, Chu S
Proc Natl Acad Sci U S A. 2015 Jun 30;112(26):7996-8001. PubMed Article
Nan X, Tamguney TM, Collisson EA, Lin LJ, Pitt C, Galeas J, Lewis S, Gray JW, McCormick F, Chu S
Proc Natl Acad Sci U S A. 2015 Jun 30;112(26):7996-8001. PubMed Article
Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 177320 | pLenti-TO/CMV-puro-DD-PAmCherry1-KRas G12D | Lentiviral vector expressing PAmCherry1-tagged KRas 4B G12D mutant, with an N-terminal dimerization domain (DD). |