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Mutation in ATG5 reduces autophagy and leads to ataxia with developmental delay
Kim M, Sandford E, Gatica D, Qiu Y, Liu X, Zheng Y, Schulman BA, Xu J, Semple I, Ro SH, Kim B, Mavioglu RN, Tolun A, Jipa A, Takats S, Karpati M, Li JZ, Yapici Z, Juhasz G, Lee JH, Klionsky DJ, Burmeister M
Elife. 2016 Jan 26;5. pii: e12245. doi: 10.7554/eLife.12245.
PubMed Article

Plasmids from Article

ID Plasmid Purpose  
111803pLU-CMV-Flag-hATG5 WTMammalian Expression of hATG5
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111804pLU-CMV-Flag-hATG5 E122DMammalian Expression of hATG5
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166851pRS416 ATG5-E141D-HA-ATG12-ATG16Expresses mutant E141D ATG5, HA-ATG12 ATG16 in yeast.
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Antibodies from Article