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Molecular basis for the dual function of Eps8 on actin dynamics: bundling and capping.
Hertzog M, Milanesi F, Hazelwood L, Disanza A, Liu H, Perlade E, Malabarba MG, Pasqualato S, Maiolica A, Confalonieri S, Le Clainche C, Offenhauser N, Block J, Rottner K, Di Fiore PP, Carlier MF, Volkmann N, Hanein D, Scita G
PLoS Biol. 2010 Jun 1;8(6):e1000387. doi: 10.1371/journal.pbio.1000387.
PubMed Article

Plasmids from Article

ID Plasmid Purpose
74786pEGFP C1-Eps8 ∆capmammalian expression of the capping activity mutant Eps8 fused to GFP
74889pEGFP C1-Eps8 ∆bundmammalian expression of the bundling activity mutant Eps8 fused to GFP
74891pEGFP C1-Eps8 ∆cap/∆bundmammalian expression of the capping and bundling activity mutant Eps8 fused to GFP
74950pEGFP C1-Eps8 WTmammalian expression of Eps8 fused to GFP

Antibodies from Article