Integrated genetic and pharmacologic interrogation of rare cancers.
Hong AL, Tseng YY, Cowley GS, Jonas O, Cheah JH, Kynnap BD, Doshi MB, Oh C, Meyer SC, Church AJ, Gill S, Bielski CM, Keskula P, Imamovic A, Howell S, Kryukov GV, Clemons PA, Tsherniak A, Vazquez F, Crompton BD, Shamji AF, Rodriguez-Galindo C, Janeway KA, Roberts CW, Stegmaier K, van Hummelen P, Cima MJ, Langer RS, Garraway LA, Schreiber SL, Root DE, Hahn WC, Boehm JS
Nat Commun. 2016 Jun 22;7:11987. doi: 10.1038/ncomms11987. PubMed Article
Hong AL, Tseng YY, Cowley GS, Jonas O, Cheah JH, Kynnap BD, Doshi MB, Oh C, Meyer SC, Church AJ, Gill S, Bielski CM, Keskula P, Imamovic A, Howell S, Kryukov GV, Clemons PA, Tsherniak A, Vazquez F, Crompton BD, Shamji AF, Rodriguez-Galindo C, Janeway KA, Roberts CW, Stegmaier K, van Hummelen P, Cima MJ, Langer RS, Garraway LA, Schreiber SL, Root DE, Hahn WC, Boehm JS
Nat Commun. 2016 Jun 22;7:11987. doi: 10.1038/ncomms11987. PubMed Article
Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 78152 | TRCN0000297275 | shCDK4 targeting 3UTR |
| 78153 | TRCN0000279887 | shCDK4 targeting CDS |
| 78154 | TRCN0000279953 | shCDK4 targeting CDS |
| 78155 | TRCN0000279952 | shCDK4 targeting 3UTR |
| 78156 | TRCN0000338399 | shXPO1 targeting CDS |
| 78157 | TRCN0000338401 | shXPO1 targeting CDS |
| 78158 | TRCN0000338462 | shXPO1 targeting CDS |
| 78159 | TRCN0000072213 | shRFP control |
| 78160 | TRCN0000072225 | shLacZ control |
| 78161 | TRCN0000072254 | Luciferase control |
| 78162 | TRCN0000231737 | Luciferase control |
| 78163 | TRCN0000231725 | shRFP control |
| 78164 | sgTP53_3 | sgTP53 |
| 78165 | sgGFP_3 | sgGFP |
| 78166 | pXPR_BRD111 | Expresses Cas9 with the pLX311 backbone |