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MutT Homolog 1 (MTH1) maintains multiple KRAS-driven pro-malignant pathways.
Patel A, Burton DG, Halvorsen K, Balkan W, Reiner T, Perez-Stable C, Cohen A, Munoz A, Giribaldi MG, Singh S, Robbins DJ, Nguyen DM, Rai P
Oncogene. 2015 May 14;34(20):2586-96. doi: 10.1038/onc.2014.195. Epub 2014 Jul 14. PubMed Article

Plasmids from Article

ID Plasmid Purpose
110918plko-tet-on puromycin-shMTH1To knock down MTH1 (Mut T Homolog 1) after addition of doxycline

Antibodies from Article