Cdk1 phosphorylates the Rac activator Tiam1 to activate centrosomal Pak and promote mitotic spindle formation.
Whalley HJ, Porter AP, Diamantopoulou Z, White GR, Castaneda-Saucedo E, Malliri A
Nat Commun. 2015 Jun 16;6:7437. doi: 10.1038/ncomms8437. PubMed Article
Whalley HJ, Porter AP, Diamantopoulou Z, White GR, Castaneda-Saucedo E, Malliri A
Nat Commun. 2015 Jun 16;6:7437. doi: 10.1038/ncomms8437. PubMed Article
Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 81176 | pRetro-XT-PAK2-CFP(puro)-WT | Retroviral vector for expression of wild-type PAK2 with a CFP fusion |
| 81179 | pRetro-XT-PAK2-CFP(puro)-T402A | Retroviral vector for expression of kinase inactive PAK2 with a CFP fusion |
| 81180 | pRetro-XT-PAK2-CFP(puro)-L107F | Retroviral vector for expression of kinase active PAK2 with a CFP fusion |