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N-terminal cleavage and release of the ectodomain of Flt1 is mediated via ADAM10 and ADAM 17 and regulated by VEGFR2 and the Flt1 intracellular domain.
Raikwar NS, Liu KZ, Thomas CP
PLoS One. 2014 Nov 11;9(11):e112794. doi: 10.1371/journal.pone.0112794. eCollection 2014.
PubMed

Plasmids from Article

ID Plasmid Purpose
86036hFLT1 delta CTDhuman VEGFR1 with deletion of the entire intracellular domain
86037hFlt1 Y1333Fhuman VEGFR1 with Y to F mutation at position 1333

Antibodies from Article