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A viral strategy for targeting and manipulating interneurons across vertebrate species.
Dimidschstein J, Chen Q, Tremblay R, Rogers SL, Saldi GA, Guo L, Xu Q, Liu R, Lu C, Chu J, Avery MC, Rashid MS, Baek M, Jacob AL, Smith GB, Wilson DE, Kosche G, Kruglikov I, Rusielewicz T, Kotak VC, Mowery TM, Anderson SA, Callaway EM, Dasen JS, Fitzpatrick D, Fossati V, Long MA, Noggle S, Reynolds JH, Sanes DH, Rudy B, Feng G, Fishell G
Nat Neurosci. 2016 Oct 31. doi: 10.1038/nn.4430.
PubMed Article

Plasmids from Article

ID Plasmid Purpose  
83894pAAV-hDlx-Flex-dTomato-Fishell_7Cre recombinase-dependent dTomato expression in forebrain GABA-ergic interneurons under the control of the hDlx enhancer element
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83895pAAV-hDlx-Flex-GFP-Fishell_6Cre recombinase-dependent GFP expression in forebrain GABA-ergic interneurons under the control of the hDlx enhancer element
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83896pAAV-hDlx-GiDREADD-dTomato-Fishell-5Gi-DREADD (P2A) nuclear dTomato expression in forebrain GABA-ergic interneurons under the control of the hDlx enhancer element
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83897pAAV-hDlx-GqDREADD-dTomato-Fishell-4Gq-DREADD (P2A) nuclear dTomato expression in forebrain GABA-ergic interneurons under the control of the hDlx enhancer element
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83898pAAV-mDlx-ChR2-mCherry-Fishell-3ChR2-mCherry fusion expression in forebrain GABA-ergic interneurons under the control of the mDlx enhancer element
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83899pAAV-mDlx-GCaMP6f-Fishell-2GCaMP6f expression in forebrain GABA-ergic interneurons under the control of the mDlx enhancer element
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83900pAAV-mDlx-GFP-Fishell-1GFP expression in forebrain GABA-ergic interneurons under the control of the mDlx enhancer element
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