The human homolog of Saccharomyces cerevisiae Apg7p is a Protein-activating enzyme for multiple substrates including human Apg12p, GATE-16, GABARAP, and MAP-LC3.
Tanida I, Tanida-Miyake E, Ueno T, Kominami E
J Biol Chem. 2001 Jan 19;276(3):1701-6. Epub 2000 Nov 28. PubMed Article
Tanida I, Tanida-Miyake E, Ueno T, Kominami E
J Biol Chem. 2001 Jan 19;276(3):1701-6. Epub 2000 Nov 28. PubMed Article
Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 87867 | pCMV-hATG7wt | Express a wild type human Atg7/Apg7 in mammalian cells |
| 87868 | pCMV-hATG7CS | Express a active-site mutant human Atg7/Apg7 C572S in mammalian cells |
| 87869 | pEGFP-hAtg12 | Express a EGFP-human Atg12/Apg12 in mammalian cells |
| 87870 | pEGFP-hGATE-16 | Express a EGFP-human GATE-16 in mammalian cells |
| 87871 | pEGFP-hGABARAP | Express a EGFP-human GABARAP in mammalian cells |
| 87872 | pEGFP-hLC3 | Express a EGFP-human MAP1-LC3 in mammalian cells |