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Somatic genome editing with CRISPR/Cas9 generates and corrects a metabolic disease.
Jarrett KE, Lee CM, Yeh YH, Hsu RH, Gupta R, Zhang M, Rodriguez PJ, Lee CS, Gillard BK, Bissig KD, Pownall HJ, Martin JF, Bao G, Lagor WR
Sci Rep. 2017 Mar 16;7:44624. doi: 10.1038/srep44624.
PubMed Article

Plasmids from Article

ID Plasmid Purpose  
890601179_pAAV-U6-BbsI-gRNA-CB-EmGFPAAV-gRNA cloning vector with GFP reporter
890611183_pAAV-U6-Ex14-gRNAd-CB-EmGFPAAV-gRNA targeting the murine Ldlr gene
890621184_pAAV-U6-ApoB-gRNA2-CB-EmGFPAAV-gRNA targeting the murine Apob gene