Skip to main content
This website uses cookies to ensure you get the best experience. By continuing to use this site, you agree to the use of cookies.

Addgene is open for ordering and depositing; find up-to-date details here. To learn more about how we are supporting COVID-19 research and to find related plasmids, check out our COVID-19 and Coronavirus Plasmids & Resources page.

Please note: Your browser does not support the features used on Addgene's website. You may not be able to create an account or request plasmids through this website until you upgrade your browser. Learn more

Please note: Your browser does not fully support some of the features used on Addgene's website. If you run into any problems registering, depositing, or ordering please contact us at [email protected] Learn more

Somatic genome editing with CRISPR/Cas9 generates and corrects a metabolic disease.
Jarrett KE, Lee CM, Yeh YH, Hsu RH, Gupta R, Zhang M, Rodriguez PJ, Lee CS, Gillard BK, Bissig KD, Pownall HJ, Martin JF, Bao G, Lagor WR
Sci Rep. 2017 Mar 16;7:44624. doi: 10.1038/srep44624.
PubMed Article

Plasmids from Article

ID Plasmid Purpose  
890601179_pAAV-U6-BbsI-gRNA-CB-EmGFPAAV-gRNA cloning vector with GFP reporter
890611183_pAAV-U6-Ex14-gRNAd-CB-EmGFPAAV-gRNA targeting the murine Ldlr gene
890621184_pAAV-U6-ApoB-gRNA2-CB-EmGFPAAV-gRNA targeting the murine Apob gene