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Optimization of the mevalonate-based isoprenoid biosynthetic pathway in Escherichia coli for production of the anti-malarial drug precursor amorpha-4,11-diene.
Anthony JR, Anthony LC, Nowroozi F, Kwon G, Newman JD, Keasling JD
Metab Eng. 2009 Jan;11(1):13-9. doi: 10.1016/j.ymben.2008.07.007. Epub 2008 Aug 12.
PubMed Article

Plasmids from Article

ID Plasmid Purpose  
100167Keasling-2187Used to improve production from engineered biosynthetic pathways include optimizing codon usage, enhancing production of rate-limiting enzymes, and eliminating the accumulation of toxic intermediates or byproducts to improve cell growth
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100168Keasling-2337Used to improve production from engineered biosynthetic pathways include optimizing codon usage, enhancing production of rate-limiting enzymes, and eliminating the accumulation of toxic intermediates or byproducts to improve cell growth
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100169JBEI-3716Used to improve production from engineered biosynthetic pathways include optimizing codon usage, enhancing production of rate-limiting enzymes, and eliminating the accumulation of toxic intermediates or byproducts to improve cell growth
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