PSPC1 mediates TGF-beta1 autocrine signalling and Smad2/3 target switching to promote EMT, stemness and metastasis.
Yeh HW, Hsu EC, Lee SS, Lang YD, Lin YC, Chang CY, Lee SY, Gu DL, Shih JH, Ho CM, Chen CF, Chen CT, Tu PH, Cheng CF, Chen RH, Yang RB, Jou YS
Nat Cell Biol. 2018 Apr;20(4):479-491. doi: 10.1038/s41556-018-0062-y. Epub 2018 Mar 28. PubMed Article
Yeh HW, Hsu EC, Lee SS, Lang YD, Lin YC, Chang CY, Lee SY, Gu DL, Shih JH, Ho CM, Chen CF, Chen CT, Tu PH, Cheng CF, Chen RH, Yang RB, Jou YS
Nat Cell Biol. 2018 Apr;20(4):479-491. doi: 10.1038/s41556-018-0062-y. Epub 2018 Mar 28. PubMed Article
Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 101760 | pGL3-p57 | p57 promoter reporter |
| 101761 | pGL3-Sox2 | Sox2 promoter reporter |
| 101762 | pGL3-TGFb1 | TGFb1 promoter reporter |
| 101763 | CS2 Flag-Smad2 (3A) | Expresses SMAD2 (3A) in mammalian cells |
| 101764 | pCDNA3-HA PSPC1 | Expresses PSPC1 in mammalian cells |