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Sestrin as a feedback inhibitor of TOR that prevents age-related pathologies.
Lee JH, Budanov AV, Park EJ, Birse R, Kim TE, Perkins GA, Ocorr K, Ellisman MH, Bodmer R, Bier E, Karin M
Science. 2010 Mar 5;327(5970):1223-8. doi: 10.1126/science.1182228. PubMed Article

Plasmids from Article

ID Plasmid Purpose
66919pGEX-4T-1 dSesn (1187)bacterial expression of dSesn
66920pUAST-Myc-mSesn2 (1186)expression of mouse Sesn2 in drosophila

Antibodies from Article