Skip to main content
This website uses cookies to ensure you get the best experience. By continuing to use this site, you agree to the use of cookies.

Please note: Your browser does not support the features used on Addgene's website. You may not be able to create an account or request plasmids through this website until you upgrade your browser. Learn more

Please note: Your browser does not fully support some of the features used on Addgene's website. If you run into any problems registering, depositing, or ordering please contact us at [email protected]. Learn more

Addgene
Spindle asymmetry drives non-Mendelian chromosome segregation.
Akera T, Chmatal L, Trimm E, Yang K, Aonbangkhen C, Chenoweth DM, Janke C, Schultz RM, Lampson MA
Science. 2017 Nov 3;358(6363):668-672. doi: 10.1126/science.aan0092. PubMed Article

Plasmids from Article

ID Plasmid Purpose
107264mouse CENP-B-EGFPmouse CENP-B-EGFP in pIVT vector for in vitro transcription
1072656x Halo-EGFP- 2x PACT6x Halo-EGFP- 2x PACT construct downstream of T7 promotor for in vitro transcription
107266mCherry-eDHFRmCherry-eDHFR in pIVT vector for in vitro transcription
107267mCherry-eDHFR-Cdc42Q61LmCherry-eDHFR-Cdc42Q61L in pIVT vector for in vitro transcription. Note that Cdc42 in this plasmid keeps its CAAX domain.

Antibodies from Article