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Mapping a functional cancer genome atlas of tumor suppressors in mouse liver using AAV-CRISPR-mediated direct in vivo screening.
Wang G, Chow RD, Ye L, Guzman CD, Dai X, Dong MB, Zhang F, Sharp PA, Platt RJ, Chen S
Sci Adv. 2018 Feb 28;4(2):eaao5508. doi: 10.1126/sciadv.aao5508. eCollection 2018 Feb.
PubMed

Plasmids from Article

ID Plasmid Purpose  
109395EFS-VectorAAV-CRISPR knockout plasmid for direct in vivo genome editing
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109396TBG-VectorAAV-CRISPR knockout plasmid with Cre recombinase driven by TBG promoter for direct in vivo genome editing in mouse liver
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113584EFS-mTSGAAV-CRISPR library for pool mutagenesis of top tumor suppressor genes
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113585TBG-mTSGAAV-CRISPR library for pool mutagenesis of top tumor suppressor genes in mouse liver
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