Skip to main content
This website uses cookies to ensure you get the best experience. By continuing to use this site, you agree to the use of cookies.

Addgene is open for ordering and depositing; find up-to-date details here. To learn more about how we are supporting COVID-19 research and to find related plasmids, check out our COVID-19 and Coronavirus Plasmids & Resources page.

Please note: Your browser does not support the features used on Addgene's website. You may not be able to create an account or request plasmids through this website until you upgrade your browser. Learn more

Please note: Your browser does not fully support some of the features used on Addgene's website. If you run into any problems registering, depositing, or ordering please contact us at [email protected] Learn more

An enhanced CRISPR repressor for targeted mammalian gene regulation.
Yeo NC, Chavez A, Lance-Byrne A, Chan Y, Menn D, Milanova D, Kuo CC, Guo X, Sharma S, Tung A, Cecchi RJ, Tuttle M, Pradhan S, Lim ET, Davidsohn N, Ebrahimkhani MR, Collins JJ, Lewis NE, Kiani S, Church GM
Nat Methods. 2018 Jul 16. pii: 10.1038/s41592-018-0048-5. doi: 10.1038/s41592-018-0048-5.
PubMed Article

Plasmids from Article

ID Plasmid Purpose  
110820dCas9-KRABConventional dCas9 repressor-dCas9-KRAB
Loading...
110821dCas9-KRAB-MeCP2Improved dCas9 repressor-dCas9-KRAB-MeCP2
Loading...
110822pB-CAGGS-dCas9-KRABPiggyBac compatible plasmid expressing dCas9-KRAB
Loading...
110823pB-CAGGS-dCas9PiggyBac compatible plasmid expressing dCas9
Loading...
110824pB-CAGGS-dCas9-KRAB-MeCP2PiggyBac compatible plasmid expressing dCas9-KRAB-MeCP2
Loading...