Addgene: Mouse medulloblastoma driven by CRISPR activation of cellular Myc.

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Mouse medulloblastoma driven by CRISPR activation of cellular Myc.
Vo BT, Kwon JA, Li C, Finkelstein D, Xu B, Orr BA, Sherr CJ, Roussel MF
Sci Rep. 2018 Jun 7;8(1):8733. doi: 10.1038/s41598-018-24956-1. PubMed

Plasmids from Article

ID	Plasmid	Purpose
114726	pT2K-CAGGS-U6-stuffer-dCAs9-VP160-T2A-IRES-mCherry	dCas9-VP160 expression in mammalian cells
114727	pT2K-CAGGS-U6-stuffer (infusion)-IRES-CFP	expression in mammalian cells
114728	pT2K-CAGGS-U6-sgRNA-M5-IRES-CFP	sgRNA targeting a sequence upstream of the initiator ATG of the cellular Myc gene
114729	pT2K-CAGGS-U6-sgRNA-M5-U6-sgRNA-M7-U6-sgRNA-M9-IRES-CFP	3 sgRNAs targeting a sequence upstream of the initiator ATG of the cellular Myc gene
114730	pT2K-CAGGS-U6-sgRNA-M7-IRES-CFP	sgRNA targeting a sequence upstream of the initiator ATG of the cellular Myc gene
114731	pT2K-CAGGS-U6-sgRNA-M9-IRES-CFP	sgRNA targeting a sequence upstream of the initiator ATG of the cellular Myc gene

Antibodies from Article