Saccharomyces cerevisiae as a platform for assessing sphingolipid lipid kinase inhibitors.
Kharel Y, Agah S, Huang T, Mendelson AJ, Eletu OT, Barkey-Bircann P, Gesualdi J, Smith JS, Santos WL, Lynch KR
PLoS One. 2018 Apr 19;13(4):e0192179. doi: 10.1371/journal.pone.0192179. eCollection 2018. PubMed
Kharel Y, Agah S, Huang T, Mendelson AJ, Eletu OT, Barkey-Bircann P, Gesualdi J, Smith JS, Santos WL, Lynch KR
PLoS One. 2018 Apr 19;13(4):e0192179. doi: 10.1371/journal.pone.0192179. eCollection 2018. PubMed
Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 118091 | HsSPHK1 | Expresses sphingosine kinase 1, which catalyzes the phosphorylation of sphingosine to sphingosine-1-phosphate (S1P) |
| 118092 | HsSPHK2 | Expresses sphingosine kinase 2, which catalyzes the phosphorylation of sphingosine to sphingosine-1-phosphate (S1P) |
| 118598 | MmSphk2 | Expresses sphingosine kinase 2, which catalyzes the phosphorylation of sphingosine to form sphingosine 1-phosphate in mice |
| 118599 | MmSphk1 | Expresses sphingosine kinase 1, which catalyzes the phosphorylation of sphingosine to form sphingosine 1-phosphate in mice |
| 118600 | HsCERK | Expresses ceramide kinase, which catalyzes the phosphorylation of ceramide to form ceramide 1-phosphate |