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Septin 11 is present in GABAergic synapses and plays a functional role in the cytoarchitecture of neurons and GABAergic synaptic connectivity.

Li X, Serwanski DR, Miralles CP, Nagata K, De Blas AL
J Biol Chem. 2009 Jun 19;284(25):17253-65. doi: 10.1074/jbc.M109.008870. Epub 2009 Apr 20. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
120314Septin 11 isoform ISeptin 11 isoform I mammalian expression
120315Septin 11 isoform IISeptin 11 isoform II mammalian expression
120316Septin 11 isoform II-EGFPSeptin 11 isoform II mammalian expression (EGFP-tag at the C-terminus)
120317EGFP-Septin 11 isoform IISeptin 11 isoform II mammalian expression (EGFP-tag at the N-terminus)
120318mCherry-Septin 11 isoform IISeptin 11 isoform II expression (mCherry-tag at the N-terminus)
120319Septin 11 isoform IIISeptin 11 isoform III mammalian expression
120320Septin 11 isoform IVSeptin 11 isoform IV mammalian expression
122020SEPT11 sh1 shRNAKnock Down of Septin 11. It targetes Septin 11 mRNA. It knocks down all known splice variants of Sept 11 mRNAs.
122021SEPT11 sh1 3m shRNANegative control shRNA for SEPT11 sh1 shRNA (plasmid 122020).
122022Rescue Septin 11 mRNARescue mRNA for Septin 11 Knock Down with sh1 shRNA. Splice variant II (EU711415) with 5 silent mutations at the SEPT11 sh1 shRNA target site.
122023SEPT11 sh2 shRNAKnock Down of Septin 11. It targets Septin 11 shRNA. It knocks down all known splice variants of Sept 11 mRNAs.
122024SEPT11 sh2 3m shRNANegative control shRNA for SEPT11 sh2 shRNA (plasmid 122023).
122025Rescue Septin 11 mRNARescue mRNA for Septin 11 Knock Down with sh2 shRNA. Splice variant II (EU711415) with 5 silent mutations at SEPT11 sh2 shRNA target site.

Antibodies from Article