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Cas9-mediated allelic exchange repairs compound heterozygous recessive mutations in mice.
Wang D, Li J, Song CQ, Tran K, Mou H, Wu PH, Tai PWL, Mendonca CA, Ren L, Wang BY, Su Q, Gessler DJ, Zamore PD, Xue W, Gao G
Nat Biotechnol. 2018 Oct;36(9):839-842. doi: 10.1038/nbt.4219. Epub 2018 Aug 13.
PubMed Article

Plasmids from Article

ID Plasmid  
121507pAAV.pU1a-SpCas9
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121508pAAVsc.U6-sgFah.CMV/CB-EGFP
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121510pAAVsc.U6-sgAspa.CMV/CB-EGFP
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121511pAAVsc.U6-sgIdua.CMV/CB-EGFP
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